Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.
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| Title: | Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits. |
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| Authors: | Blaazer AR; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Orrling KM; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands TI Pharma, Leiden, The Netherlands., Shanmugham A; IOTA Pharmaceuticals, Cambridge, UK., Jansen C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands University of Dundee, Dundee, UK., Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Belgium., Edink E; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Sterk GJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Siderius M; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., England P; IOTA Pharmaceuticals, Cambridge, UK., Bailey D; IOTA Pharmaceuticals, Cambridge, UK., de Esch IJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands r.leurs@vu.nl. |
| Source: | Journal of biomolecular screening [J Biomol Screen] 2015 Jan; Vol. 20 (1), pp. 131-40. Date of Electronic Publication: 2014 Sep 17. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Sage Publications Country of Publication: United States NLM ID: 9612112 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-454X (Electronic) Linking ISSN: 10870571 NLM ISO Abbreviation: J Biomol Screen Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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