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Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.

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Title: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
Authors: Bjornsson HT; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. hbjorns1@jhmi.edu., Benjamin JS; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Zhang L; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Weissman J; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Kennedy Krieger Institute, Baltimore, MD 21205, USA., Gerber EE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Chen YC; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Vaurio RG; Kennedy Krieger Institute, Baltimore, MD 21205, USA., Potter MC; Brain Science Institute, Neurology Department, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Hansen KD; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Department of Biostatistics, Bloomberg School of Public Health, Baltimore, MD 21205, USA., Dietz HC; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Howard Hughes Medical Institute, Baltimore, MD 21205, USA.
Source: Science translational medicine [Sci Transl Med] 2014 Oct 01; Vol. 6 (256), pp. 256ra135.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Bjornsson+HT%22">Bjornsson HT</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. hbjorns1@jhmi.edu.<br /><searchLink fieldCode="AU" term="%22Benjamin+JS%22">Benjamin JS</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Weissman+J%22">Weissman J</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Kennedy Krieger Institute, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Gerber+EE%22">Gerber EE</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Vaurio+RG%22">Vaurio RG</searchLink>; Kennedy Krieger Institute, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Potter+MC%22">Potter MC</searchLink>; Brain Science Institute, Neurology Department, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Hansen+KD%22">Hansen KD</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Department of Biostatistics, Bloomberg School of Public Health, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Dietz+HC%22">Dietz HC</searchLink>; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. Howard Hughes Medical Institute, Baltimore, MD 21205, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2014 Oct 01; Vol. 6 (256), pp. 256ra135.
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