Genetic and epigenetic fine mapping of causal autoimmune disease variants.

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Title: Genetic and epigenetic fine mapping of causal autoimmune disease variants.
Authors: Farh KK; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Marson A; Diabetes Center and Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, California 94143, USA., Zhu J; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Kleinewietfeld M; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA., Housley WJ; Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA., Beik S; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Shoresh N; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Whitton H; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Ryan RJ; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA., Shishkin AA; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] California Institute of Technology, 1200 E California Boulevard, Pasadena, California 91125, USA., Hatan M; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Carrasco-Alfonso MJ; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Mayer D; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Luckey CJ; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA., Patsopoulos NA; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02142, USA [3] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA., De Jager PL; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02142, USA [3] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA., Kuchroo VK; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA., Epstein CB; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA., Daly MJ; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA., Hafler DA; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA., Bernstein BE; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
Source: Nature [Nature] 2015 Feb 19; Vol. 518 (7539), pp. 337-43. Date of Electronic Publication: 2014 Oct 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Farh+KK%22">Farh KK</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.<br /><searchLink fieldCode="AU" term="%22Marson+A%22">Marson A</searchLink>; Diabetes Center and Division of Infectious Diseases, Department of Medicine, University of California, San Francisco, California 94143, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.<br /><searchLink fieldCode="AU" term="%22Kleinewietfeld+M%22">Kleinewietfeld M</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Housley+WJ%22">Housley WJ</searchLink>; Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Beik+S%22">Beik S</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Shoresh+N%22">Shoresh N</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Whitton+H%22">Whitton H</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Ryan+RJ%22">Ryan RJ</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.<br /><searchLink fieldCode="AU" term="%22Shishkin+AA%22">Shishkin AA</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] California Institute of Technology, 1200 E California Boulevard, Pasadena, California 91125, USA.<br /><searchLink fieldCode="AU" term="%22Hatan+M%22">Hatan M</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Carrasco-Alfonso+MJ%22">Carrasco-Alfonso MJ</searchLink>; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.<br /><searchLink fieldCode="AU" term="%22Mayer+D%22">Mayer D</searchLink>; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.<br /><searchLink fieldCode="AU" term="%22Luckey+CJ%22">Luckey CJ</searchLink>; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.<br /><searchLink fieldCode="AU" term="%22Patsopoulos+NA%22">Patsopoulos NA</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02142, USA [3] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22De+Jager+PL%22">De Jager PL</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02142, USA [3] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Kuchroo+VK%22">Kuchroo VK</searchLink>; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Epstein+CB%22">Epstein CB</searchLink>; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.<br /><searchLink fieldCode="AU" term="%22Daly+MJ%22">Daly MJ</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.<br /><searchLink fieldCode="AU" term="%22Hafler+DA%22">Hafler DA</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut 06511, USA.<br /><searchLink fieldCode="AU" term="%22Bernstein+BE%22">Bernstein BE</searchLink>; 1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA [2] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA [3] Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [4] Center for Systems Biology and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
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