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Electrophilicity of pyridazine-3-carbonitrile, pyrimidine-2-carbonitrile, and pyridine-carbonitrile derivatives: a chemical model to describe the formation of thiazoline derivatives in human liver microsomes.

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Title: Electrophilicity of pyridazine-3-carbonitrile, pyrimidine-2-carbonitrile, and pyridine-carbonitrile derivatives: a chemical model to describe the formation of thiazoline derivatives in human liver microsomes.
Authors: Sinha S; Pharmaceutical Candidate Optimization, ‡Medicinal Chemistry Department, and §Advanced Biotechnology Department, Biocon Bristol-Myers Squibb R&D Center (BBRC), Syngene International Ltd , Plot No. 2 & 3, Bommasandra IV Phase, Jigani Link Road, Bangalore 560100, India., Ahire D, Wagh S, Mullick D, Sistla R, Selvakumar K, Cortes JC, Putlur SP, Mandlekar S, Johnson BM
Source: Chemical research in toxicology [Chem Res Toxicol] 2014 Dec 15; Vol. 27 (12), pp. 2052-61. Date of Electronic Publication: 2014 Dec 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Electrophilicity of pyridazine-3-carbonitrile, pyrimidine-2-carbonitrile, and pyridine-carbonitrile derivatives: a chemical model to describe the formation of thiazoline derivatives in human liver microsomes.
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  Data: <searchLink fieldCode="AU" term="%22Sinha+S%22">Sinha S</searchLink>; Pharmaceutical Candidate Optimization, ‡Medicinal Chemistry Department, and §Advanced Biotechnology Department, Biocon Bristol-Myers Squibb R&D Center (BBRC), Syngene International Ltd , Plot No. 2 & 3, Bommasandra IV Phase, Jigani Link Road, Bangalore 560100, India.<br /><searchLink fieldCode="AU" term="%22Ahire+D%22">Ahire D</searchLink><br /><searchLink fieldCode="AU" term="%22Wagh+S%22">Wagh S</searchLink><br /><searchLink fieldCode="AU" term="%22Mullick+D%22">Mullick D</searchLink><br /><searchLink fieldCode="AU" term="%22Sistla+R%22">Sistla R</searchLink><br /><searchLink fieldCode="AU" term="%22Selvakumar+K%22">Selvakumar K</searchLink><br /><searchLink fieldCode="AU" term="%22Cortes+JC%22">Cortes JC</searchLink><br /><searchLink fieldCode="AU" term="%22Putlur+SP%22">Putlur SP</searchLink><br /><searchLink fieldCode="AU" term="%22Mandlekar+S%22">Mandlekar S</searchLink><br /><searchLink fieldCode="AU" term="%22Johnson+BM%22">Johnson BM</searchLink>
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  Data: <searchLink fieldCode="JN" term="%228807448%22">Chemical research in toxicology</searchLink> [Chem Res Toxicol] 2014 Dec 15; Vol. 27 (12), pp. 2052-61. <i>Date of Electronic Publication: </i>2014 Dec 02.
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        Value: 10.1021/tx500256j
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      – TitleFull: Electrophilicity of pyridazine-3-carbonitrile, pyrimidine-2-carbonitrile, and pyridine-carbonitrile derivatives: a chemical model to describe the formation of thiazoline derivatives in human liver microsomes.
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              Text: 2014 Dec 15
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