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OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.

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Title: OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.
Authors: Buchan S; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Manzo T; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Flutter B; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Rogel A; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Edwards N; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Zhang L; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Sivakumaran S; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Ghorashian S; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Carpenter B; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Bennett C; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School., Sykes M; Columbia Center for Translational Immunology, Columbia University Medical Center, New York., Croft M; Institute of Allergy and Immunology, La Jolla., Al-Shamkhani A; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Chakraverty R; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Jan 01; Vol. 194 (1), pp. 125-133. Date of Electronic Publication: 2014 Nov 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.
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  Data: <searchLink fieldCode="AU" term="%22Buchan+S%22">Buchan S</searchLink>; Cancer Sciences Unit, Faculty of Medicine, University of Southampton.<br /><searchLink fieldCode="AU" term="%22Manzo+T%22">Manzo T</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Flutter+B%22">Flutter B</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Rogel+A%22">Rogel A</searchLink>; Cancer Sciences Unit, Faculty of Medicine, University of Southampton.<br /><searchLink fieldCode="AU" term="%22Edwards+N%22">Edwards N</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Sivakumaran+S%22">Sivakumaran S</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Ghorashian+S%22">Ghorashian S</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Carpenter+B%22">Carpenter B</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Bennett+C%22">Bennett C</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.<br /><searchLink fieldCode="AU" term="%22Freeman+GJ%22">Freeman GJ</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School.<br /><searchLink fieldCode="AU" term="%22Sykes+M%22">Sykes M</searchLink>; Columbia Center for Translational Immunology, Columbia University Medical Center, New York.<br /><searchLink fieldCode="AU" term="%22Croft+M%22">Croft M</searchLink>; Institute of Allergy and Immunology, La Jolla.<br /><searchLink fieldCode="AU" term="%22Al-Shamkhani+A%22">Al-Shamkhani A</searchLink>; Cancer Sciences Unit, Faculty of Medicine, University of Southampton.<br /><searchLink fieldCode="AU" term="%22Chakraverty+R%22">Chakraverty R</searchLink>; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London.
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  Data: <searchLink fieldCode="JN" term="%222985117R%22">Journal of immunology (Baltimore, Md. : 1950)</searchLink> [J Immunol] 2015 Jan 01; Vol. 194 (1), pp. 125-133. <i>Date of Electronic Publication: </i>2014 Nov 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985117R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1550-6606 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221767%22">00221767 </searchLink><i>NLM ISO Abbreviation: </i>J Immunol <i>Subsets: </i>MEDLINE
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