OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence.
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| Title: | OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. |
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| Authors: | Buchan S; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Manzo T; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Flutter B; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Rogel A; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Edwards N; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Zhang L; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Sivakumaran S; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Ghorashian S; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Carpenter B; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Bennett C; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School., Sykes M; Columbia Center for Translational Immunology, Columbia University Medical Center, New York., Croft M; Institute of Allergy and Immunology, La Jolla., Al-Shamkhani A; Cancer Sciences Unit, Faculty of Medicine, University of Southampton., Chakraverty R; Transplantation Immunology Group, Cancer Institute and Institute for Immunity and Transplantation, University College London. |
| Source: | Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2015 Jan 01; Vol. 194 (1), pp. 125-133. Date of Electronic Publication: 2014 Nov 17. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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