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Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.

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Title: Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.
Authors: Henze AT; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany., Garvalov BK; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany., Seidel S; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany., Cuesta AM; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany., Ritter M; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany., Filatova A; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany., Foss F; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany., Dopeso H; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany., Essmann CL; Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany., Maxwell PH; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK., Reifenberger G; Institute of Neuropathology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Carmeliet P; Vesalius Research Center (VRC), Angiogenesis and Neurovascular Link Laboratory, University of Leuven, Leuven B-3000, Belgium., Acker-Palmer A; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany., Acker T; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.
Source: Nature communications [Nat Commun] 2014 Nov 25; Vol. 5, pp. 5582. Date of Electronic Publication: 2014 Nov 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Henze+AT%22">Henze AT</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Garvalov+BK%22">Garvalov BK</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Seidel+S%22">Seidel S</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Cuesta+AM%22">Cuesta AM</searchLink>; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Ritter+M%22">Ritter M</searchLink>; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Filatova+A%22">Filatova A</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Foss+F%22">Foss F</searchLink>; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Dopeso+H%22">Dopeso H</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Essmann+CL%22">Essmann CL</searchLink>; Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Maxwell+PH%22">Maxwell PH</searchLink>; Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Reifenberger+G%22">Reifenberger G</searchLink>; Institute of Neuropathology, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Carmeliet+P%22">Carmeliet P</searchLink>; Vesalius Research Center (VRC), Angiogenesis and Neurovascular Link Laboratory, University of Leuven, Leuven B-3000, Belgium.<br /><searchLink fieldCode="AU" term="%22Acker-Palmer+A%22">Acker-Palmer A</searchLink>; 1] Institute of Cell Biology and Neuroscience, Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60438 Frankfurt, Germany [2] Focus Program Translational Neurosciences (FTN), University of Mainz, 55131 Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Acker+T%22">Acker T</searchLink>; Institute of Neuropathology, University of Giessen, 35392 Giessen, Germany.
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