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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.

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Title: Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.
Authors: Herbst RS; Yale Comprehensive Cancer Center, Yale School of Medicine, 333 Cedar Street, WWW221, New Haven, Connecticut 06520, USA., Soria JC; Gustave Roussy South-Paris University, 114 Rue Edouard Vaillant, 94805 Villefuij, Cedex, France., Kowanetz M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Fine GD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Hamid O; The Angeles Clinic and Research Institute, 11818 Wilshire Blvd, Los Angeles, California 90025, USA., Gordon MS; Pinnacle Oncology Hematology, 9055 E Del Camino Dr 100, Scottsdale, Arizona 85258, USA., Sosman JA; Vanderbilt-Ingram Cancer Center, 2220 Pierce Avenue, Nashville, Tennessee 37212, USA., McDermott DF; Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Shapiro 9, Boston, Massachusetts 02215, USA., Powderly JD; Carolina BioOncology Institute, 9801 W. Kincey Ave, Suite 145, Huntersville, North Carolina 28078, USA., Gettinger SN; Yale Comprehensive Cancer Center, Yale School of Medicine, 333 Cedar Street, WWW221, New Haven, Connecticut 06520, USA., Kohrt HE; Stanford University, CCSR Bldg Room 1110, Stanford, California 94305, USA., Horn L; Vanderbilt-Ingram Cancer Center, 1301 Medical Center Dr, Suite 1710, Nashville, Tennessee 37212, USA., Lawrence DP; Massachusetts General Hospital, 55 Fruit Street, YAW 9E, Boston, Massachusetts 02114, USA., Rost S; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Leabman M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Xiao Y; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Mokatrin A; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Koeppen H; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Hegde PS; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Mellman I; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Chen DS; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA., Hodi FS; Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
Source: Nature [Nature] 2014 Nov 27; Vol. 515 (7528), pp. 563-7.
Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Herbst+RS%22">Herbst RS</searchLink>; Yale Comprehensive Cancer Center, Yale School of Medicine, 333 Cedar Street, WWW221, New Haven, Connecticut 06520, USA.<br /><searchLink fieldCode="AU" term="%22Soria+JC%22">Soria JC</searchLink>; Gustave Roussy South-Paris University, 114 Rue Edouard Vaillant, 94805 Villefuij, Cedex, France.<br /><searchLink fieldCode="AU" term="%22Kowanetz+M%22">Kowanetz M</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Fine+GD%22">Fine GD</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hamid+O%22">Hamid O</searchLink>; The Angeles Clinic and Research Institute, 11818 Wilshire Blvd, Los Angeles, California 90025, USA.<br /><searchLink fieldCode="AU" term="%22Gordon+MS%22">Gordon MS</searchLink>; Pinnacle Oncology Hematology, 9055 E Del Camino Dr 100, Scottsdale, Arizona 85258, USA.<br /><searchLink fieldCode="AU" term="%22Sosman+JA%22">Sosman JA</searchLink>; Vanderbilt-Ingram Cancer Center, 2220 Pierce Avenue, Nashville, Tennessee 37212, USA.<br /><searchLink fieldCode="AU" term="%22McDermott+DF%22">McDermott DF</searchLink>; Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Shapiro 9, Boston, Massachusetts 02215, USA.<br /><searchLink fieldCode="AU" term="%22Powderly+JD%22">Powderly JD</searchLink>; Carolina BioOncology Institute, 9801 W. Kincey Ave, Suite 145, Huntersville, North Carolina 28078, USA.<br /><searchLink fieldCode="AU" term="%22Gettinger+SN%22">Gettinger SN</searchLink>; Yale Comprehensive Cancer Center, Yale School of Medicine, 333 Cedar Street, WWW221, New Haven, Connecticut 06520, USA.<br /><searchLink fieldCode="AU" term="%22Kohrt+HE%22">Kohrt HE</searchLink>; Stanford University, CCSR Bldg Room 1110, Stanford, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Horn+L%22">Horn L</searchLink>; Vanderbilt-Ingram Cancer Center, 1301 Medical Center Dr, Suite 1710, Nashville, Tennessee 37212, USA.<br /><searchLink fieldCode="AU" term="%22Lawrence+DP%22">Lawrence DP</searchLink>; Massachusetts General Hospital, 55 Fruit Street, YAW 9E, Boston, Massachusetts 02114, USA.<br /><searchLink fieldCode="AU" term="%22Rost+S%22">Rost S</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Leabman+M%22">Leabman M</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Xiao+Y%22">Xiao Y</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Mokatrin+A%22">Mokatrin A</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Koeppen+H%22">Koeppen H</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hegde+PS%22">Hegde PS</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Mellman+I%22">Mellman I</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Chen+DS%22">Chen DS</searchLink>; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, USA.<br /><searchLink fieldCode="AU" term="%22Hodi+FS%22">Hodi FS</searchLink>; Dana-Farber/Brigham and Women's Cancer Center, 450 Brookline Avenue, Boston, Massachusetts 02215, USA.
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