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Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

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Title: Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
Authors: Wang LS; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Naj AC; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia., Graham RR; Department of Human Genetics, Genentech Inc, South San Francisco, California., Crane PK; Department of Medicine, University of Washington, Seattle., Kunkle BW; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida., Cruchaga C; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri7Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri., Murcia JD; Department of Biology, Brigham Young University, Provo, Utah., Cannon-Albright L; Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City10George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah., Baldwin CT; Biomedical Genetics, Department of Medicine, Boston University, Boston, Massachusetts., Zetterberg H; Institute of Neurology, University College London, London, England13Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska Uni., Blennow K; Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden., Kukull WA; Department of Epidemiology, University of Washington, Seattle., Faber KM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis., Schupf N; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York17Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York18Gertrude H. Sergievsky Center, Columbia., Norton MC; Department of Family, Consumer, and Human Development, Utah State University, Logan20Department of Psychology, Utah State University, Logan., Tschanz JT; Department of Psychology, Utah State University, Logan., Munger RG; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan., Corcoran CD; Department of Mathematics and Statistics, Utah State University, Logan., Rogaeva E; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Lin CF; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Dombroski BA; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Cantwell LB; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Partch A; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Valladares O; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Hakonarson H; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., St George-Hyslop P; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada25Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, England., Green RC; Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts., Goate AM; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri7Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri., Foroud TM; Department of Medical and Molecular Genetics, Indiana University, Indianapolis., Carney RM; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida., Larson EB; Department of Medicine, University of Washington, Seattle28Group Health Research Institute, Seattle, Washington., Behrens TW; Department of Human Genetics, Genentech Inc, South San Francisco, California., Kauwe JS; Department of Biology, Brigham Young University, Provo, Utah., Haines JL; Center for Human Genetics and Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee., Farrer LA; Department of Biology, Brigham Young University, Provo, Utah30Department of Biostatistics, Boston University, Boston, Massachusetts31Department of Ophthalmology, Boston University, Boston, Massachusetts32Department of Neurology, Boston University, Boston., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida34Dr John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida., Mayeux R; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York18Gertrude H. Sergievsky Center, Columbia University, New York, New York35Department of Neurology, Columbia University, New York, New York., Schellenberg GD; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia., Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L
Corporate Authors: Alzheimer's Disease Genetics Consortium, National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study
Source: JAMA neurology [JAMA Neurol] 2015 Feb; Vol. 72 (2), pp. 209-16.
Publication Type: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
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  Data: <searchLink fieldCode="AU" term="%22Wang+LS%22">Wang LS</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Naj+AC%22">Naj AC</searchLink>; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Graham+RR%22">Graham RR</searchLink>; Department of Human Genetics, Genentech Inc, South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Crane+PK%22">Crane PK</searchLink>; Department of Medicine, University of Washington, Seattle.<br /><searchLink fieldCode="AU" term="%22Kunkle+BW%22">Kunkle BW</searchLink>; John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri7Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Murcia+JD%22">Murcia JD</searchLink>; Department of Biology, Brigham Young University, Provo, Utah.<br /><searchLink fieldCode="AU" term="%22Cannon-Albright+L%22">Cannon-Albright L</searchLink>; Division of Genetic Epidemiology, Department of Medicine, University of Utah School of Medicine, Salt Lake City10George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah.<br /><searchLink fieldCode="AU" term="%22Baldwin+CT%22">Baldwin CT</searchLink>; Biomedical Genetics, Department of Medicine, Boston University, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Zetterberg+H%22">Zetterberg H</searchLink>; Institute of Neurology, University College London, London, England13Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska Uni.<br /><searchLink fieldCode="AU" term="%22Blennow+K%22">Blennow K</searchLink>; Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Kukull+WA%22">Kukull WA</searchLink>; Department of Epidemiology, University of Washington, Seattle.<br /><searchLink fieldCode="AU" term="%22Faber+KM%22">Faber KM</searchLink>; Department of Medical and Molecular Genetics, Indiana University, Indianapolis.<br /><searchLink fieldCode="AU" term="%22Schupf+N%22">Schupf N</searchLink>; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York17Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York18Gertrude H. Sergievsky Center, Columbia.<br /><searchLink fieldCode="AU" term="%22Norton+MC%22">Norton MC</searchLink>; Department of Family, Consumer, and Human Development, Utah State University, Logan20Department of Psychology, Utah State University, Logan.<br /><searchLink fieldCode="AU" term="%22Tschanz+JT%22">Tschanz JT</searchLink>; Department of Psychology, Utah State University, Logan.<br /><searchLink fieldCode="AU" term="%22Munger+RG%22">Munger RG</searchLink>; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan.<br /><searchLink fieldCode="AU" term="%22Corcoran+CD%22">Corcoran CD</searchLink>; Department of Mathematics and Statistics, Utah State University, Logan.<br /><searchLink fieldCode="AU" term="%22Rogaeva+E%22">Rogaeva E</searchLink>; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lin+CF%22">Lin CF</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Dombroski+BA%22">Dombroski BA</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Cantwell+LB%22">Cantwell LB</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Partch+A%22">Partch A</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Valladares+O%22">Valladares O</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22St+George-Hyslop+P%22">St George-Hyslop P</searchLink>; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada25Cambridge Institute for Medical Research, Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.<br /><searchLink fieldCode="AU" term="%22Green+RC%22">Green RC</searchLink>; Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Goate+AM%22">Goate AM</searchLink>; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri7Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St Louis, Missouri.<br /><searchLink fieldCode="AU" term="%22Foroud+TM%22">Foroud TM</searchLink>; Department of Medical and Molecular Genetics, Indiana University, Indianapolis.<br /><searchLink fieldCode="AU" term="%22Carney+RM%22">Carney RM</searchLink>; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida.<br /><searchLink fieldCode="AU" term="%22Larson+EB%22">Larson EB</searchLink>; Department of Medicine, University of Washington, Seattle28Group Health Research Institute, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Behrens+TW%22">Behrens TW</searchLink>; Department of Human Genetics, Genentech Inc, South San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Kauwe+JS%22">Kauwe JS</searchLink>; Department of Biology, Brigham Young University, Provo, Utah.<br /><searchLink fieldCode="AU" term="%22Haines+JL%22">Haines JL</searchLink>; Center for Human Genetics and Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Farrer+LA%22">Farrer LA</searchLink>; Department of Biology, Brigham Young University, Provo, Utah30Department of Biostatistics, Boston University, Boston, Massachusetts31Department of Ophthalmology, Boston University, Boston, Massachusetts32Department of Neurology, Boston University, Boston.<br /><searchLink fieldCode="AU" term="%22Pericak-Vance+MA%22">Pericak-Vance MA</searchLink>; John P. 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  Data: <searchLink fieldCode="CA" term="%22Alzheimer's+Disease+Genetics+Consortium%22">Alzheimer's Disease Genetics Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22National+Institute+on+Aging-Late-Onset+Alzheimer%27s+Disease+%28NIA-LOAD%29+Family+Study%22">National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101589536%22">JAMA neurology</searchLink> [JAMA Neurol] 2015 Feb; Vol. 72 (2), pp. 209-16.
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  Data: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101589536 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2168-6157 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221686149%22">21686149 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Neurol <i>Subsets: </i>MEDLINE
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        Value: 10.1001/jamaneurol.2014.2157
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      – TitleFull: Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
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    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2015 Feb
              Type: published
              Y: 2015
          Identifiers:
            – Type: issn-electronic
              Value: 2168-6157
          Numbering:
            – Type: volume
              Value: 72
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: JAMA neurology
              Type: main
ResultId 1