Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

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Title: Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
Authors: Mengelbier LH; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Karlsson J; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Lindgren D; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Valind A; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Lilljebjörn H; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Jansson C; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Bexell D; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Braekeveldt N; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Ameur A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, SE75003 Uppsala, Sweden., Jonson T; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Kultima HG; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Isaksson A; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Asmundsson J; Department of Pathology, Karolinska University Hospital, SE17176 Solna, Sweden., Versteeg R; Department of Human Genetics, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands., Rissler M; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Fioretos T; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Sandstedt B; Division of Pediatric Oncology, Department of Women's and Children's Health, Karolinska Institute, SE17165 Solna, Sweden., Börjesson A; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Backman T; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Pal N; Astrid Lindgren Children's Hospital, Karolinska University Hospital, SE17176 Solna, Sweden., Øra I; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Mayrhofer M; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Gisselsson D; 1] Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden [2] Department of Pathology, Skåne Regional and University Laboratories, SE22185 Lund, Sweden.
Source: Nature communications [Nat Commun] 2015 Jan 27; Vol. 6, pp. 6125. Date of Electronic Publication: 2015 Jan 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/ncomms7125