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Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.

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Title: Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
Authors: Mengelbier LH; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Karlsson J; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Lindgren D; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Valind A; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Lilljebjörn H; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Jansson C; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Bexell D; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Braekeveldt N; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden., Ameur A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, SE75003 Uppsala, Sweden., Jonson T; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Kultima HG; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Isaksson A; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Asmundsson J; Department of Pathology, Karolinska University Hospital, SE17176 Solna, Sweden., Versteeg R; Department of Human Genetics, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands., Rissler M; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Fioretos T; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden., Sandstedt B; Division of Pediatric Oncology, Department of Women's and Children's Health, Karolinska Institute, SE17165 Solna, Sweden., Börjesson A; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Backman T; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Pal N; Astrid Lindgren Children's Hospital, Karolinska University Hospital, SE17176 Solna, Sweden., Øra I; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden., Mayrhofer M; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden., Gisselsson D; 1] Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden [2] Department of Pathology, Skåne Regional and University Laboratories, SE22185 Lund, Sweden.
Source: Nature communications [Nat Commun] 2015 Jan 27; Vol. 6, pp. 6125. Date of Electronic Publication: 2015 Jan 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Mengelbier+LH%22">Mengelbier LH</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Karlsson+J%22">Karlsson J</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Lindgren+D%22">Lindgren D</searchLink>; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Valind+A%22">Valind A</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Lilljebjörn+H%22">Lilljebjörn H</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jansson+C%22">Jansson C</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Bexell+D%22">Bexell D</searchLink>; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Braekeveldt+N%22">Braekeveldt N</searchLink>; Translational Cancer Research, Department of Laboratory Medicine, Lund University, Medicon Village 404-406, SE22363 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Ameur+A%22">Ameur A</searchLink>; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, SE75003 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Jonson+T%22">Jonson T</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Kultima+HG%22">Kultima HG</searchLink>; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Isaksson+A%22">Isaksson A</searchLink>; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Asmundsson+J%22">Asmundsson J</searchLink>; Department of Pathology, Karolinska University Hospital, SE17176 Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Versteeg+R%22">Versteeg R</searchLink>; Department of Human Genetics, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rissler+M%22">Rissler M</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Fioretos+T%22">Fioretos T</searchLink>; Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sandstedt+B%22">Sandstedt B</searchLink>; Division of Pediatric Oncology, Department of Women's and Children's Health, Karolinska Institute, SE17165 Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Börjesson+A%22">Börjesson A</searchLink>; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Backman+T%22">Backman T</searchLink>; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Pal+N%22">Pal N</searchLink>; Astrid Lindgren Children's Hospital, Karolinska University Hospital, SE17176 Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Øra+I%22">Øra I</searchLink>; Department of Pediatrics, Lund University, University Hospital, SE22185 Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Mayrhofer+M%22">Mayrhofer M</searchLink>; Array and Analysis Facility, Department of Medical Sciences, Uppsala University, SE75003 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Gisselsson+D%22">Gisselsson D</searchLink>; 1] Department of Clinical Genetics, Lund University, Biomedical Center C13, SE22184 Lund, Sweden [2] Department of Pathology, Skåne Regional and University Laboratories, SE22185 Lund, Sweden.
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