An acetyl-methyl switch drives a conformational change in p53.

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Title: An acetyl-methyl switch drives a conformational change in p53.
Authors: Tong Q; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Mazur SJ; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Rincon-Arano H; Basic Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Rothbart SB; Department of Biochemistry and Biophysics and the Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA., Kuznetsov DM; Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210, USA., Cui G; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Liu WH; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Gete Y; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Klein BJ; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA., Jenkins L; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Mer G; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Kutateladze AG; Department of Chemistry and Biochemistry, University of Denver, Denver, CO 80210, USA., Strahl BD; Department of Biochemistry and Biophysics and the Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA., Groudine M; Basic Science Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Radiation Oncology, University Washington School of Medicine, Seattle, WA 98109, USA., Appella E; Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, MD 20892, USA., Kutateladze TG; Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: tatiana.kutateladze@ucdenver.edu.
Source: Structure (London, England : 1993) [Structure] 2015 Feb 03; Vol. 23 (2), pp. 322-31.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-4186
DOI:10.1016/j.str.2014.12.010