View in EDS PDF Full Text

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Saved in:
Bibliographic Details
Title: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.
Authors: Kenny HA; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Lal-Nag M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA., White EA; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Shen M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA., Chiang CY; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Mitra AK; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Zhang Y; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Curtis M; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Schryver EM; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Bettis S; Institute of Genomics and Systems Biology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA., Jadhav A; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA., Boxer MB; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA., Li Z; 1] Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA [2] Lead Discovery and Optimization, Bristol-Myers Squibb, 5 Research Parkway, Wallingford, Connecticut 06492, USA., Ferrer M; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA., Lengyel E; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.
Source: Nature communications [Nat Commun] 2015 Feb 05; Vol. 6, pp. 6220. Date of Electronic Publication: 2015 Feb 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 25653139
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Kenny+HA%22">Kenny HA</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Lal-Nag+M%22">Lal-Nag M</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22White+EA%22">White EA</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Chiang+CY%22">Chiang CY</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Mitra+AK%22">Mitra AK</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Curtis+M%22">Curtis M</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Schryver+EM%22">Schryver EM</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Bettis+S%22">Bettis S</searchLink>; Institute of Genomics and Systems Biology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.<br /><searchLink fieldCode="AU" term="%22Jadhav+A%22">Jadhav A</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Boxer+MB%22">Boxer MB</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; 1] Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA [2] Lead Discovery and Optimization, Bristol-Myers Squibb, 5 Research Parkway, Wallingford, Connecticut 06492, USA.<br /><searchLink fieldCode="AU" term="%22Ferrer+M%22">Ferrer M</searchLink>; Division of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, 9800 Medical Center Drive, Building B, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Lengyel+E%22">Lengyel E</searchLink>; Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, University of Chicago, 5841 South Maryland Avenue, MC2050, Chicago, Illinois 60637, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2015 Feb 05; Vol. 6, pp. 6220. <i>Date of Electronic Publication: </i>2015 Feb 05.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=25653139
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/ncomms7220
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 6220
    Titles:
      – TitleFull: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Kenny HA
      – PersonEntity:
          Name:
            NameFull: Lal-Nag M
      – PersonEntity:
          Name:
            NameFull: White EA
      – PersonEntity:
          Name:
            NameFull: Shen M
      – PersonEntity:
          Name:
            NameFull: Chiang CY
      – PersonEntity:
          Name:
            NameFull: Mitra AK
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Curtis M
      – PersonEntity:
          Name:
            NameFull: Schryver EM
      – PersonEntity:
          Name:
            NameFull: Bettis S
      – PersonEntity:
          Name:
            NameFull: Jadhav A
      – PersonEntity:
          Name:
            NameFull: Boxer MB
      – PersonEntity:
          Name:
            NameFull: Li Z
      – PersonEntity:
          Name:
            NameFull: Ferrer M
      – PersonEntity:
          Name:
            NameFull: Lengyel E
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 05
              M: 02
              Text: 2015 Feb 05
              Type: published
              Y: 2015
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 6
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1