Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly.

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Title: Structures of the Gβ-CCT and PhLP1-Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly.
Authors: Plimpton RL; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602;, Cuéllar J; Centro Nacional de Biotecnología, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain; and., Lai CW; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602;, Aoba T; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602;, Makaju A; Department of Internal Medicine, Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT 84112., Franklin S; Department of Internal Medicine, Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT 84112., Mathis AD; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602;, Prince JT; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602;, Carrascosa JL; Centro Nacional de Biotecnología, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain; and., Valpuesta JM; Centro Nacional de Biotecnología, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain; and bmwillardson@chem.byu.edu jmv@cnb.csic.es., Willardson BM; Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602; bmwillardson@chem.byu.edu jmv@cnb.csic.es.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Feb 24; Vol. 112 (8), pp. 2413-8. Date of Electronic Publication: 2015 Feb 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1419595112