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Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis.

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Title: Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis.
Authors: McKerrell T; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Park N; Sequencing Research Group, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Moreno T; Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, 39011 Santander, Spain., Grove CS; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Ponstingl H; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Stephens J; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK., Crawley C; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK., Craig J; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK., Scott MA; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK., Hodkinson C; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Cambridge Blood and Stem Cell Biobank, Department of Haematology, University of Cambridge, Cambridge CB2 0XY, UK., Baxter J; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Cambridge Blood and Stem Cell Biobank, Department of Haematology, University of Cambridge, Cambridge CB2 0XY, UK., Rad R; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, 81675 München, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Forsyth DR; Department of Medicine for the Elderly, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK., Quail MA; Sequencing Research Group, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Zeggini E; Human Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Ouwehand W; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK; Human Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK., Varela I; Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, 39011 Santander, Spain., Vassiliou GS; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK. Electronic address: gsv20@sanger.ac.uk.
Corporate Authors: Understanding Society Scientific Group
Source: Cell reports [Cell Rep] 2015 Mar 03; Vol. 10 (8), pp. 1239-45. Date of Electronic Publication: 2015 Feb 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22McKerrell+T%22">McKerrell T</searchLink>; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Park+N%22">Park N</searchLink>; Sequencing Research Group, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Moreno+T%22">Moreno T</searchLink>; Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, 39011 Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Grove+CS%22">Grove CS</searchLink>; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Ponstingl+H%22">Ponstingl H</searchLink>; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Stephens+J%22">Stephens J</searchLink>; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK.<br /><searchLink fieldCode="AU" term="%22Crawley+C%22">Crawley C</searchLink>; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Craig+J%22">Craig J</searchLink>; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Scott+MA%22">Scott MA</searchLink>; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Hodkinson+C%22">Hodkinson C</searchLink>; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Cambridge Blood and Stem Cell Biobank, Department of Haematology, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Baxter+J%22">Baxter J</searchLink>; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Cambridge Blood and Stem Cell Biobank, Department of Haematology, University of Cambridge, Cambridge CB2 0XY, UK.<br /><searchLink fieldCode="AU" term="%22Rad+R%22">Rad R</searchLink>; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, 81675 München, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Forsyth+DR%22">Forsyth DR</searchLink>; Department of Medicine for the Elderly, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK.<br /><searchLink fieldCode="AU" term="%22Quail+MA%22">Quail MA</searchLink>; Sequencing Research Group, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Zeggini+E%22">Zeggini E</searchLink>; Human Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Ouwehand+W%22">Ouwehand W</searchLink>; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK; Human Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Varela+I%22">Varela I</searchLink>; Instituto de Biomedicina y Biotecnología de Cantabria (CSIC-UC-Sodercan), Departamento de Biología Molecular, Universidad de Cantabria, 39011 Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Vassiliou+GS%22">Vassiliou GS</searchLink>; Haematological Cancer Genetics, Wellcome Trust Sanger Institute, Cambridge CB10 1SA, UK; Department of Haematology, Cambridge Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, UK; Department of Haematology, Cambridge University Hospitals NHS Trust, Cambridge CB2 0QQ, UK. Electronic address: gsv20@sanger.ac.uk.
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