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Liver-directed lentiviral gene therapy in a dog model of hemophilia B.

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Title: Liver-directed lentiviral gene therapy in a dog model of hemophilia B.
Authors: Cantore A; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy., Ranzani M; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy., Bartholomae CC; Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, 69120 Heidelberg, Germany., Volpin M; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy., Valle PD; Coagulation Service and Thrombosis Research Unit, San Raffaele Scientific Institute, 20132 Milan, Italy., Sanvito F; Pathology Unit, Department of Oncology, San Raffaele Scientific Institute, 20132 Milan, Italy., Sergi LS; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy., Gallina P; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy., Benedicenti F; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy., Bellinger D; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Raymer R; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Merricks E; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Bellintani F; MolMed S.p.A., 20132 Milan, Italy., Martin S; Généthon, 91000 Évry, France., Doglioni C; Pathology Unit, Department of Oncology, San Raffaele Scientific Institute, 20132 Milan, Italy., D'Angelo A; Coagulation Service and Thrombosis Research Unit, San Raffaele Scientific Institute, 20132 Milan, Italy., VandenDriessche T; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, 1050 Brussels, Belgium. Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium., Chuah MK; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, 1050 Brussels, Belgium. Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium., Schmidt M; Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, 69120 Heidelberg, Germany., Nichols T; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Montini E; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy., Naldini L; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy. naldini.luigi@hsr.it.
Source: Science translational medicine [Sci Transl Med] 2015 Mar 04; Vol. 7 (277), pp. 277ra28.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Liver-directed lentiviral gene therapy in a dog model of hemophilia B.
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  Data: <searchLink fieldCode="AU" term="%22Cantore+A%22">Cantore A</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ranzani+M%22">Ranzani M</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bartholomae+CC%22">Bartholomae CC</searchLink>; Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Volpin+M%22">Volpin M</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Valle+PD%22">Valle PD</searchLink>; Coagulation Service and Thrombosis Research Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sanvito+F%22">Sanvito F</searchLink>; Pathology Unit, Department of Oncology, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sergi+LS%22">Sergi LS</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gallina+P%22">Gallina P</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Benedicenti+F%22">Benedicenti F</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bellinger+D%22">Bellinger D</searchLink>; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Raymer+R%22">Raymer R</searchLink>; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Merricks+E%22">Merricks E</searchLink>; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Bellintani+F%22">Bellintani F</searchLink>; MolMed S.p.A., 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Martin+S%22">Martin S</searchLink>; Généthon, 91000 Évry, France.<br /><searchLink fieldCode="AU" term="%22Doglioni+C%22">Doglioni C</searchLink>; Pathology Unit, Department of Oncology, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22D'Angelo+A%22">D'Angelo A</searchLink>; Coagulation Service and Thrombosis Research Unit, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22VandenDriessche+T%22">VandenDriessche T</searchLink>; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, 1050 Brussels, Belgium. Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Chuah+MK%22">Chuah MK</searchLink>; Department of Gene Therapy and Regenerative Medicine, Free University of Brussels, 1050 Brussels, Belgium. Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, University of Leuven, 3000 Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Schmidt+M%22">Schmidt M</searchLink>; Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center, 69120 Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Nichols+T%22">Nichols T</searchLink>; Department of Pathology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Montini+E%22">Montini E</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Naldini+L%22">Naldini L</searchLink>; San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, 20132 Milan, Italy. Vita-Salute San Raffaele University, 20132 Milan, Italy. naldini.luigi@hsr.it.
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