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A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury.

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Title: A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury.
Authors: Whidbey C; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA., Vornhagen J; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA., Gendrin C; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA., Boldenow E; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA., Samson JM; Department of Physics, University of Washington, Seattle, WA, USA., Doering K; Department of Physics, University of Washington, Seattle, WA, USA., Ngo L; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA., Ezekwe EA Jr; Department of Medicine, Division of Infectious Diseases and Pharmacology, School of Medicine and Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gundlach JH; Department of Physics, University of Washington, Seattle, WA, USA., Elovitz MA; Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women's Health Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, USA., Liggitt D; Department of Comparative Medicine, School of Medicine University of Washington, Seattle, WA, USA., Duncan JA; Department of Medicine, Division of Infectious Diseases and Pharmacology, School of Medicine and Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Adams Waldorf KM; Department of Obstetrics and Gynecology, School of Medicine University of Washington, Seattle, WA, USA., Rajagopal L; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA lakshmi.rajagopal@seattlechildrens.org.
Source: EMBO molecular medicine [EMBO Mol Med] 2015 Apr; Vol. 7 (4), pp. 488-505.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury.
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  Data: <searchLink fieldCode="AU" term="%22Whidbey+C%22">Whidbey C</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Vornhagen+J%22">Vornhagen J</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Gendrin+C%22">Gendrin C</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Boldenow+E%22">Boldenow E</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Samson+JM%22">Samson JM</searchLink>; Department of Physics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Doering+K%22">Doering K</searchLink>; Department of Physics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ngo+L%22">Ngo L</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ezekwe+EA+Jr%22">Ezekwe EA Jr</searchLink>; Department of Medicine, Division of Infectious Diseases and Pharmacology, School of Medicine and Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gundlach+JH%22">Gundlach JH</searchLink>; Department of Physics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Elovitz+MA%22">Elovitz MA</searchLink>; Maternal and Child Health Research Program, Department of Obstetrics and Gynecology, Center for Research on Reproduction and Women's Health Perelman School of Medicine University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Liggitt+D%22">Liggitt D</searchLink>; Department of Comparative Medicine, School of Medicine University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Duncan+JA%22">Duncan JA</searchLink>; Department of Medicine, Division of Infectious Diseases and Pharmacology, School of Medicine and Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Adams+Waldorf+KM%22">Adams Waldorf KM</searchLink>; Department of Obstetrics and Gynecology, School of Medicine University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Rajagopal+L%22">Rajagopal L</searchLink>; Department of Pediatric Infectious Diseases, University of Washington and Seattle Children's Research Institute, Seattle, WA, USA Department of Global Health, University of Washington, Seattle, WA, USA lakshmi.rajagopal@seattlechildrens.org.
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