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Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness.

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Title: Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness.
Authors: Katajisto P; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA. Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland. pekka.katajisto@helsinki.fi sabatini@wi.mit.edu., Döhla J; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland., Chaffer CL; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA., Pentinmikko N; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland., Marjanovic N; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA., Iqbal S; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland., Zoncu R; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA., Chen W; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA., Weinberg RA; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA., Sabatini DM; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA. Broad Institute, Cambridge, MA 02142, USA. The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA. pekka.katajisto@helsinki.fi sabatini@wi.mit.edu.
Source: Science (New York, N.Y.) [Science] 2015 Apr 17; Vol. 348 (6232), pp. 340-3. Date of Electronic Publication: 2015 Apr 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Katajisto+P%22">Katajisto P</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA. Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland. pekka.katajisto@helsinki.fi sabatini@wi.mit.edu.<br /><searchLink fieldCode="AU" term="%22Döhla+J%22">Döhla J</searchLink>; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Chaffer+CL%22">Chaffer CL</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Pentinmikko+N%22">Pentinmikko N</searchLink>; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Marjanovic+N%22">Marjanovic N</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Iqbal+S%22">Iqbal S</searchLink>; Institute of Biotechnology, University of Helsinki, P.O. Box 00014, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Zoncu+R%22">Zoncu R</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Chen+W%22">Chen W</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Weinberg+RA%22">Weinberg RA</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Sabatini+DM%22">Sabatini DM</searchLink>; Whitehead Institute for Biomedical Research, Boston, MA 02142, USA. Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA. Howard Hughes Medical Institute, MIT, Cambridge, MA 02139, USA. Broad Institute, Cambridge, MA 02142, USA. The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA. pekka.katajisto@helsinki.fi sabatini@wi.mit.edu.
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