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Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.

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Title: Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Authors: Sainz B Jr; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain., Alcala S; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain., Garcia E; Molecular Diagnostics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Pathology Department, Hospital Universitario Fundacion Alcorcon, Madrid, Spain., Sanchez-Ripoll Y; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Azevedo MM; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Cioffi M; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Tatari M; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Miranda-Lorenzo I; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Hidalgo M; Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Gomez-Lopez G; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Cañamero M; Histopathology Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Erkan M; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany Koc University School of Medicine, Istanbul, Turkey., Kleeff J; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany., García-Silva S; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Sancho P; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Hermann PC; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Deptartment of Internal Medicine I, Ulm University, Ulm, Germany., Heeschen C; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London, UK.
Source: Gut [Gut] 2015 Dec; Vol. 64 (12), pp. 1921-35. Date of Electronic Publication: 2015 Apr 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
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  Data: <searchLink fieldCode="AU" term="%22Sainz+B+Jr%22">Sainz B Jr</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Alcala+S%22">Alcala S</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia+E%22">Garcia E</searchLink>; Molecular Diagnostics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Pathology Department, Hospital Universitario Fundacion Alcorcon, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sanchez-Ripoll+Y%22">Sanchez-Ripoll Y</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Azevedo+MM%22">Azevedo MM</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cioffi+M%22">Cioffi M</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Tatari+M%22">Tatari M</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Miranda-Lorenzo+I%22">Miranda-Lorenzo I</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Hidalgo+M%22">Hidalgo M</searchLink>; Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gomez-Lopez+G%22">Gomez-Lopez G</searchLink>; Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Cañamero+M%22">Cañamero M</searchLink>; Histopathology Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Erkan+M%22">Erkan M</searchLink>; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany Koc University School of Medicine, Istanbul, Turkey.<br /><searchLink fieldCode="AU" term="%22Kleeff+J%22">Kleeff J</searchLink>; Department of Surgery, Klinikum rechts der Isar, Technical University, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22García-Silva+S%22">García-Silva S</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Sancho+P%22">Sancho P</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Hermann+PC%22">Hermann PC</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Deptartment of Internal Medicine I, Ulm University, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Heeschen+C%22">Heeschen C</searchLink>; Stem Cells and Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London, UK.
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