Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.

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Bibliographic Details
Title: Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.
Authors: Guyenet SJ; Department of Medicine (Medical Genetics) and., Mookerjee SS; The Buck Institute for Research on Aging, Novato, CA 94945, USA., Lin A; The Buck Institute for Research on Aging, Novato, CA 94945, USA., Custer SK; Department of Medicine (Medical Genetics) and., Chen SF; The Buck Institute for Research on Aging, Novato, CA 94945, USA., Sopher BL; Department of Neurology, University of Washington, Seattle, WA, USA., La Spada AR; Department of Medicine (Medical Genetics) and Department of Cellular and Molecular Medicine, Division of Biological Sciences, Institute for Genomic Medicine, and the Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA, Department of Neurosciences, Division of Biological Sciences, Institute for Genomic Medicine, and the Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA, Department of Pediatrics, Division of Biological Sciences, Institute for Genomic Medicine, and the Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, CA, USA and Rady Children's Hospital, San Diego, CA 92123, USA alaspada@ucsd.edu lellerby@buckinstitute.org., Ellerby LM; The Buck Institute for Research on Aging, Novato, CA 94945, USA, alaspada@ucsd.edu lellerby@buckinstitute.org.
Source: Human molecular genetics [Hum Mol Genet] 2015 Jul 15; Vol. 24 (14), pp. 3908-17. Date of Electronic Publication: 2015 Apr 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2083
DOI:10.1093/hmg/ddv121