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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

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Title: Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
Authors: Najm FJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Madhavan M; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Zaremba A; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Shick E; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Karl RT; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Factor DC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Miller TE; 1] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [2] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [3] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA., Nevin ZS; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Kantor C; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Sargent A; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Quick KL; PerkinElmer, 940 Winter Street, Waltham, Massachusetts 02451, USA., Schlatzer DM; Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Tang H; Drug Discovery Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA., Papoian R; Drug Discovery Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA., Brimacombe KR; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA., Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA., Boxer MB; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA., Jadhav A; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA., Robinson AP; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA., Podojil JR; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA., Miller SD; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA., Miller RH; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Tesar PJ; 1] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [2] Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Source: Nature [Nature] 2015 Jun 11; Vol. 522 (7555), pp. 216-20. Date of Electronic Publication: 2015 Apr 20.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Najm+FJ%22">Najm FJ</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Madhavan+M%22">Madhavan M</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Zaremba+A%22">Zaremba A</searchLink>; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Shick+E%22">Shick E</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Karl+RT%22">Karl RT</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Factor+DC%22">Factor DC</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Miller+TE%22">Miller TE</searchLink>; 1] Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [2] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA [3] Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.<br /><searchLink fieldCode="AU" term="%22Nevin+ZS%22">Nevin ZS</searchLink>; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Kantor+C%22">Kantor C</searchLink>; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Sargent+A%22">Sargent A</searchLink>; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Quick+KL%22">Quick KL</searchLink>; PerkinElmer, 940 Winter Street, Waltham, Massachusetts 02451, USA.<br /><searchLink fieldCode="AU" term="%22Schlatzer+DM%22">Schlatzer DM</searchLink>; Center for Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Tang+H%22">Tang H</searchLink>; Drug Discovery Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA.<br /><searchLink fieldCode="AU" term="%22Papoian+R%22">Papoian R</searchLink>; Drug Discovery Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45237, USA.<br /><searchLink fieldCode="AU" term="%22Brimacombe+KR%22">Brimacombe KR</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Shen+M%22">Shen M</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Boxer+MB%22">Boxer MB</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Jadhav+A%22">Jadhav A</searchLink>; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, Maryland 20850, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+AP%22">Robinson AP</searchLink>; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA.<br /><searchLink fieldCode="AU" term="%22Podojil+JR%22">Podojil JR</searchLink>; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Avenue, Chicago, Illinois 60611, USA.<br /><searchLink fieldCode="AU" term="%22Miller+SD%22">Miller SD</searchLink>; Department of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, 303 E. 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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2015 Jun 11; Vol. 522 (7555), pp. 216-20. <i>Date of Electronic Publication: </i>2015 Apr 20.
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