BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.
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| Title: | BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells. |
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| Authors: | Baker EK; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia.; Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, 3065 VIC, Australia., Taylor S; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia., Gupte A; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia., Sharp PP; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Walia M; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia., Walsh NC; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia.; Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, 3065 VIC, Australia., Zannettino AC; Myeloma Research Laboratory, School of Medical Sciences, Faculty of Health Sciences, University of Adelaide, Adelaide, SA 5005, Australia and Cancer Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia., Chalk AM; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia.; Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, 3065 VIC, Australia., Burns CJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; The University of Melbourne, Department of Medical Biology, 3010 VIC, Australia., Walkley CR; St. Vincent's Institute, Fitzroy, 3065 VIC, Australia.; Department of Medicine, St. Vincent's Hospital, University of Melbourne, Fitzroy, 3065 VIC, Australia.; ACRF Rational Drug Discovery Centre, St. Vincent's Institute, Fitzroy, 3065 VIC, Australia. |
| Source: | Scientific reports [Sci Rep] 2015 May 06; Vol. 5, pp. 10120. Date of Electronic Publication: 2015 May 06. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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