Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells.
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| Title: | Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, Leads to Altered Carbohydrate Metabolism in Cancer Cells. |
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| Authors: | Tan B; Discovery Chemistry, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Dong S; Cancer Research, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Shepard RL; Cancer Research, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Kays L; Cancer Research, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Roth KD; Discovery Chemistry, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Geeganage S; Cancer Research, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285., Kuo MS; Discovery Chemistry, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285. Electronic address: Kuo_Ming-Shang@Lilly.com., Zhao G; Cancer Research, Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285. Electronic address: Zhao_Genshi@Lilly.com. |
| Source: | The Journal of biological chemistry [J Biol Chem] 2015 Jun 19; Vol. 290 (25), pp. 15812-15824. Date of Electronic Publication: 2015 May 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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