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Spatial genomic heterogeneity within localized, multifocal prostate cancer.

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Title: Spatial genomic heterogeneity within localized, multifocal prostate cancer.
Authors: Boutros PC; 1] Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [3] Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Fraser M; Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Harding NJ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., de Borja R; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Trudel D; Department of Pathology and Laboratory Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada., Lalonde E; 1] Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Meng A; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Ontario, Canada., Hennings-Yeomans PH; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., McPherson A; School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada., Sabelnykova VY; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Zia A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Fox NS; 1] Ontario Institute for Cancer Research, Toronto, Ontario, Canada. [2] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Livingstone J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Shiah YJ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Wang J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Beck TA; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Have CL; Department of Pathology and Laboratory Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada., Chong T; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sam M; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Johns J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Timms L; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Buchner N; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Wong A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Watson JD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Simmons TT; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., P'ng C; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Zafarana G; Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Nguyen F; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Luo X; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chu KC; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Prokopec SD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Sykes J; Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Dal Pra A; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Berlin A; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada., Brown A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chan-Seng-Yue MA; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yousif F; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Denroche RE; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chong LC; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chen GM; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Jung E; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Fung C; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Starmans MH; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Chen H; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Govind SK; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Hawley J; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., D'Costa A; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Pintilie M; Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Waggott D; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Hach F; School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada., Lambin P; Department of Radiotherapy, Maastricht University, Maastricht, the Netherlands., Muthuswamy LB; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Cooper C; 1] Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK. [2] Department of Biological Sciences, University of East Anglia, Norwich, UK. [3] School of Medicine, University of East Anglia, Norwich, UK., Eeles R; 1] Division of Genetics and Epidemiology, The Institute of Cancer Research, Sutton, UK. [2] Royal Marsden National Health Service (NHS) Foundation Trust, London and Sutton, UK., Neal D; 1] Urological Research Laboratory, Cancer Research UK Cambridge Research Institute, Cambridge, UK. [2] Department of Surgical Oncology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK., Tetu B; Department of Pathology, Laval University, Quebec City, Quebec, Canada., Sahinalp C; School of Computing Science, Simon Fraser University, Burnaby, British Columbia, Canada., Stein LD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Fleshner N; Division of Urology, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada., Shah SP; 1] Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada. [2] Department of Computer Science, University of British Columbia, Vancouver, British Columbia, Canada. [3] British Columbia Cancer Agency Research Centre, Vancouver, British Columbia, Canada., Collins CC; 1] Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada. [2] Laboratory for Advanced Genome Analysis, Vancouver Prostate Centre, Vancouver, British Columbia, Canada., Hudson TJ; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., McPherson JD; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., van der Kwast T; Department of Pathology and Laboratory Medicine, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada., Bristow RG; 1] Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. [2] Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. [3] Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.
Source: Nature genetics [Nat Genet] 2015 Jul; Vol. 47 (7), pp. 736-45. Date of Electronic Publication: 2015 May 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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      – PersonEntity:
          Name:
            NameFull: Stein LD
      – PersonEntity:
          Name:
            NameFull: Fleshner N
      – PersonEntity:
          Name:
            NameFull: Shah SP
      – PersonEntity:
          Name:
            NameFull: Collins CC
      – PersonEntity:
          Name:
            NameFull: Hudson TJ
      – PersonEntity:
          Name:
            NameFull: McPherson JD
      – PersonEntity:
          Name:
            NameFull: van der Kwast T
      – PersonEntity:
          Name:
            NameFull: Bristow RG
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2015 Jul
              Type: published
              Y: 2015
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 47
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1