PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice. - Ghonim MA; Pyakurel K; Ibba SV; Wang J; Rodriguez P; Al-Khami AA; Lammi MR; Kim H; Zea AH; Davis C; Okpechi S; Wyczechowska D; et al. (Clinical science (London, England : 1979), 2015)