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Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.

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Title: Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.
Authors: Tsimikas S; University of California San Diego, La Jolla, CA, USA; Isis Pharmaceuticals, Carlsbad, CA, USA. Electronic address: stsimikas@ucsd.edu., Viney NJ; Isis Pharmaceuticals, Carlsbad, CA, USA., Hughes SG; Isis Pharmaceuticals, Carlsbad, CA, USA., Singleton W; Isis Pharmaceuticals, Carlsbad, CA, USA., Graham MJ; Isis Pharmaceuticals, Carlsbad, CA, USA., Baker BF; Isis Pharmaceuticals, Carlsbad, CA, USA., Burkey JL; Isis Pharmaceuticals, Carlsbad, CA, USA., Yang Q; Isis Pharmaceuticals, Carlsbad, CA, USA., Marcovina SM; University of Washington, Seattle, WA, USA., Geary RS; Isis Pharmaceuticals, Carlsbad, CA, USA., Crooke RM; Isis Pharmaceuticals, Carlsbad, CA, USA., Witztum JL; University of California San Diego, La Jolla, CA, USA.
Source: Lancet (London, England) [Lancet] 2015 Oct 10; Vol. 386 (10002), pp. 1472-83. Date of Electronic Publication: 2015 Jul 22.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study.
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  Data: <searchLink fieldCode="AU" term="%22Tsimikas+S%22">Tsimikas S</searchLink>; University of California San Diego, La Jolla, CA, USA; Isis Pharmaceuticals, Carlsbad, CA, USA. Electronic address: stsimikas@ucsd.edu.<br /><searchLink fieldCode="AU" term="%22Viney+NJ%22">Viney NJ</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hughes+SG%22">Hughes SG</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Singleton+W%22">Singleton W</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Graham+MJ%22">Graham MJ</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Baker+BF%22">Baker BF</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Burkey+JL%22">Burkey JL</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Q%22">Yang Q</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Marcovina+SM%22">Marcovina SM</searchLink>; University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Geary+RS%22">Geary RS</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Crooke+RM%22">Crooke RM</searchLink>; Isis Pharmaceuticals, Carlsbad, CA, USA.<br /><searchLink fieldCode="AU" term="%22Witztum+JL%22">Witztum JL</searchLink>; University of California San Diego, La Jolla, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%222985213R%22">Lancet (London, England)</searchLink> [Lancet] 2015 Oct 10; Vol. 386 (10002), pp. 1472-83. <i>Date of Electronic Publication: </i>2015 Jul 22.
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  Data: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985213R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-547X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201406736%22">01406736 </searchLink><i>NLM ISO Abbreviation: </i>Lancet <i>Subsets: </i>MEDLINE
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        Value: 10.1016/S0140-6736(15)61252-1
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              Text: 2015 Oct 10
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