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Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.

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Title: Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
Authors: Marques AR; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Aten J; Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Ottenhoff R; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., van Roomen CP; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Herrera Moro D; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Claessen N; Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Vinueza Veloz MF; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands., Zhou K; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands., Lin Z; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands., Mirzaian M; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., Boot RG; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands., De Zeeuw CI; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Dutch Academy of Arts & Sciences, 1105 BA, Amsterdam, The Netherlands., Overkleeft HS; Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands., Yildiz Y; Department of Internal Medicine, Hospital of Bregenz, 6900, Bregenz, Austria., Aerts JM; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands; Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands.
Source: PloS one [PLoS One] 2015 Aug 14; Vol. 10 (8), pp. e0135889. Date of Electronic Publication: 2015 Aug 14 (Print Publication: 2015).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
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  Data: <searchLink fieldCode="AU" term="%22Marques+AR%22">Marques AR</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Aten+J%22">Aten J</searchLink>; Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ottenhoff+R%22">Ottenhoff R</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Roomen+CP%22">van Roomen CP</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Herrera+Moro+D%22">Herrera Moro D</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Claessen+N%22">Claessen N</searchLink>; Department of Pathology, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vinueza+Veloz+MF%22">Vinueza Veloz MF</searchLink>; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zhou+K%22">Zhou K</searchLink>; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lin+Z%22">Lin Z</searchLink>; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mirzaian+M%22">Mirzaian M</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Boot+RG%22">Boot RG</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22De+Zeeuw+CI%22">De Zeeuw CI</searchLink>; Department of Neuroscience, Erasmus MC, 3000 CA, Rotterdam, The Netherlands; Netherlands Institute for Neuroscience, Royal Dutch Academy of Arts & Sciences, 1105 BA, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Overkleeft+HS%22">Overkleeft HS</searchLink>; Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Yildiz+Y%22">Yildiz Y</searchLink>; Department of Internal Medicine, Hospital of Bregenz, 6900, Bregenz, Austria.<br /><searchLink fieldCode="AU" term="%22Aerts+JM%22">Aerts JM</searchLink>; Department of Medical Biochemistry, Academic Medical Center, 1105 AZ, Amsterdam, The Netherlands; Leiden Institute of Chemistry, Leiden University, 2300 RA, Leiden, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2015 Aug 14; Vol. 10 (8), pp. e0135889. <i>Date of Electronic Publication: </i>2015 Aug 14 (<i>Print Publication: </i>2015).
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