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Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy.

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Title: Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy.
Authors: Rodenko B; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.uk., Wanner MJ; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands., Alkhaldi AA; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Department of Biology, College of Science, Aljouf University, Skaka, Kingdom of Saudi Arabia., Ebiloma GU; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom., Barnes RL; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom., Kaiser M; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland., Brun R; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland., McCulloch R; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom., Koomen GJ; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands., de Koning HP; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.uk.
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Nov; Vol. 59 (11), pp. 6708-16. Date of Electronic Publication: 2015 Aug 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
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  Data: Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy.
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  Data: <searchLink fieldCode="AU" term="%22Rodenko+B%22">Rodenko B</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.uk.<br /><searchLink fieldCode="AU" term="%22Wanner+MJ%22">Wanner MJ</searchLink>; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Alkhaldi+AA%22">Alkhaldi AA</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Department of Biology, College of Science, Aljouf University, Skaka, Kingdom of Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Ebiloma+GU%22">Ebiloma GU</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Barnes+RL%22">Barnes RL</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaiser+M%22">Kaiser M</searchLink>; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brun+R%22">Brun R</searchLink>; Swiss Tropical and Public Health Institute, Basel, Switzerland University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22McCulloch+R%22">McCulloch R</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Koomen+GJ%22">Koomen GJ</searchLink>; Van 't Hoff Institute for Molecular Sciences, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Koning+HP%22">de Koning HP</searchLink>; College of Medical, Veterinary and Life Sciences, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom boris.rodenko@glasgow.ac.uk harry.de-koning@glasgow.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2015 Nov; Vol. 59 (11), pp. 6708-16. <i>Date of Electronic Publication: </i>2015 Aug 17.
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              Text: 2015 Nov
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