Targeting the parasite's DNA with methyltriazenyl purine analogs is a safe, selective, and efficacious antitrypanosomal strategy. - Rodenko B; Wanner MJ; Alkhaldi AA; Ebiloma GU; Barnes RL; Kaiser M; Brun R; McCulloch R; Koomen GJ; de Koning HP (Antimicrobial agents and chemotherapy, 2015)