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Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.

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Title: Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.
Authors: Rothman DM; Department of Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: deborah.rothman@novartis.com., Gao X; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., George E; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Rasmusson T; Department of Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Bhatia D; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Alimov I; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Wang L; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Kamel A; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Hatsis P; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Feng Y; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Tutter A; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Michaud G; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., McDonald E 3rd; Department of Oncology, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Venkatesan K; Department of Oncology, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Farley D; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Digan ME; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Ni Y; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Harbinski F; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Gunduz M; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Wilson CJ; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Buckler A; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Labow M; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Tallarico J; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Myer VE; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Porter JA; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA., Wang S; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: shaowen.wang@novartis.com.
Source: Chemistry & biology [Chem Biol] 2015 Sep 17; Vol. 22 (9), pp. 1228-37. Date of Electronic Publication: 2015 Sep 10.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9500160 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1301 (Electronic) Linking ISSN: 10745521 NLM ISO Abbreviation: Chem Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Rothman+DM%22">Rothman DM</searchLink>; Department of Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: deborah.rothman@novartis.com.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22George+E%22">George E</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Rasmusson+T%22">Rasmusson T</searchLink>; Department of Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Bhatia+D%22">Bhatia D</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Alimov+I%22">Alimov I</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kamel+A%22">Kamel A</searchLink>; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Hatsis+P%22">Hatsis P</searchLink>; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Feng+Y%22">Feng Y</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Tutter+A%22">Tutter A</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Michaud+G%22">Michaud G</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22McDonald+E+3rd%22">McDonald E 3rd</searchLink>; Department of Oncology, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Venkatesan+K%22">Venkatesan K</searchLink>; Department of Oncology, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Farley+D%22">Farley D</searchLink>; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Digan+ME%22">Digan ME</searchLink>; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Ni+Y%22">Ni Y</searchLink>; Center for Proteomic Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Harbinski+F%22">Harbinski F</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Gunduz+M%22">Gunduz M</searchLink>; Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+CJ%22">Wilson CJ</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Buckler+A%22">Buckler A</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Labow+M%22">Labow M</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Tallarico+J%22">Tallarico J</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Myer+VE%22">Myer VE</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Porter+JA%22">Porter JA</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: shaowen.wang@novartis.com.
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