Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.

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Title: Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation.
Authors: Cohen ES; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Scott IC; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Majithiya JB; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Rapley L; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Kemp BP; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., England E; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Rees DG; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Overed-Sayer CL; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Woods J; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Bond NJ; Department of Biopharmaceutical Development, Analytical Biotechnology, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Veyssier CS; Department of Biopharmaceutical Development, Analytical Biotechnology, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Embrey KJ; Department of Discovery Sciences, Innovative Medicines, AstraZeneca, Mereside, Alderley Park, SK10 4TG, UK., Sims DA; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland 20878, USA., Snaith MR; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Vousden KA; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Strain MD; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Chan DT; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Carmen S; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Huntington CE; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Flavell L; Department of Discovery Sciences, Innovative Medicines, AstraZeneca, Mereside, Alderley Park, SK10 4TG, UK., Xu J; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Popovic B; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Brightling CE; Department of Infection, Immunity and Inflammation, Institute for Lung Health, Leicester LE3 9QP, UK; NIHR Respiratory Biomedical Research Unit, University Hospitals of Leicester, Leicester LE3 9QP, UK., Vaughan TJ; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Butler R; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Lowe DC; Department of Antibody Discovery and Protein Engineering, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Higazi DR; Department of Biopharmaceutical Development, Analytical Biotechnology, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Corkill DJ; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., May RD; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Sleeman MA; Department of Respiratory, Inflammation and Autoimmunity, MedImmune Ltd, Granta Park, Great Abington, CB21 6GH, UK., Mustelin T; Department of Respiratory, Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, Maryland 20878, USA.
Source: Nature communications [Nat Commun] 2015 Sep 14; Vol. 6, pp. 8327. Date of Electronic Publication: 2015 Sep 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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