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Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.

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Title: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Authors: Reddy A; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Growney JD; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Wilson NS; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Emery CM; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Johnson JA; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Ward R; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Monaco KA; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Korn J; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Monahan JE; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Stump MD; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Mapa FA; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Wilson CJ; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Steiger J; Horizon CombinatoRx, Cambridge, MA, United States of America., Ledell J; Horizon CombinatoRx, Cambridge, MA, United States of America., Rickles RJ; Horizon CombinatoRx, Cambridge, MA, United States of America., Myer VE; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Ettenberg SA; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Schlegel R; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Sellers WR; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Huet HA; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America., Lehár J; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.
Source: PloS one [PLoS One] 2015 Sep 17; Vol. 10 (9), pp. e0138486. Date of Electronic Publication: 2015 Sep 17 (Print Publication: 2015).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
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  Data: <searchLink fieldCode="AU" term="%22Reddy+A%22">Reddy A</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Growney+JD%22">Growney JD</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Wilson+NS%22">Wilson NS</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Emery+CM%22">Emery CM</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Johnson+JA%22">Johnson JA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Ward+R%22">Ward R</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Monaco+KA%22">Monaco KA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Korn+J%22">Korn J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Monahan+JE%22">Monahan JE</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Stump+MD%22">Stump MD</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Mapa+FA%22">Mapa FA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Wilson+CJ%22">Wilson CJ</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Steiger+J%22">Steiger J</searchLink>; Horizon CombinatoRx, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Ledell+J%22">Ledell J</searchLink>; Horizon CombinatoRx, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Rickles+RJ%22">Rickles RJ</searchLink>; Horizon CombinatoRx, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Myer+VE%22">Myer VE</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Ettenberg+SA%22">Ettenberg SA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Schlegel+R%22">Schlegel R</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Sellers+WR%22">Sellers WR</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Huet+HA%22">Huet HA</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.<br /><searchLink fieldCode="AU" term="%22Lehár+J%22">Lehár J</searchLink>; Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2015 Sep 17; Vol. 10 (9), pp. e0138486. <i>Date of Electronic Publication: </i>2015 Sep 17 (<i>Print Publication: </i>2015).
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