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(13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.

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Title: (13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
Authors: Dzien P; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Tee SS; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Kettunen MI; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Lyons SK; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Larkin TJ; Department of Biochemistry, University of Cambridge, Cambridge, UK., Timm KN; Department of Biochemistry, University of Cambridge, Cambridge, UK., Hu DE; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Wright A; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Rodrigues TB; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Serrao EM; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Marco-Rius I; Department of Biochemistry, University of Cambridge, Cambridge, UK., Mannion E; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., D'Santos P; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK., Kennedy BW; Department of Biochemistry, University of Cambridge, Cambridge, UK., Brindle KM; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.
Source: Magnetic resonance in medicine [Magn Reson Med] 2016 Aug; Vol. 76 (2), pp. 391-401. Date of Electronic Publication: 2015 Sep 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8505245 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-2594 (Electronic) Linking ISSN: 07403194 NLM ISO Abbreviation: Magn Reson Med Subsets: MEDLINE
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  Data: (13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Dzien+P%22">Dzien P</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Tee+SS%22">Tee SS</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kettunen+MI%22">Kettunen MI</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Lyons+SK%22">Lyons SK</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Larkin+TJ%22">Larkin TJ</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Timm+KN%22">Timm KN</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hu+DE%22">Hu DE</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Wright+A%22">Wright A</searchLink>; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Rodrigues+TB%22">Rodrigues TB</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Serrao+EM%22">Serrao EM</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Marco-Rius+I%22">Marco-Rius I</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Mannion+E%22">Mannion E</searchLink>; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22D'Santos+P%22">D'Santos P</searchLink>; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kennedy+BW%22">Kennedy BW</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Brindle+KM%22">Brindle KM</searchLink>; Department of Biochemistry, University of Cambridge, Cambridge, UK.; Cancer Research UK, Cambridge Research Institute, Li Ka Shing Centre, Cambridge, UK.
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