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Genome-wide autozygosity is associated with lower general cognitive ability.

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Title: Genome-wide autozygosity is associated with lower general cognitive ability.
Authors: Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge Center, Cambridge, MA, USA., Simonson MA; Division of Data Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA., Davies G; Department of Psychology, University of Edinburgh, Edinburgh, UK., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Tenesa A; Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit, Western General Hospital, University of Edinburgh, Edinburgh, UK.; The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Liewald DC; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Deary IJ; Department of Psychology, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., McRae A; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia., Wright MJ; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia., Montgomery GW; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia., Hansell N; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia., Martin NG; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia., Payton A; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, UK., Horan M; Centre for Clinical and Cognitive Neurosciences, Institute of Brain Behaviour and Mental Health, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK., Ollier WE; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, UK., Abdellaoui A; Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands.; Neuroscience Campus Amsterdam, Amsterdam, The Netherlands., Boomsma DI; Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands.; Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.; EMGO+ Institute for Health and Care Research, Amsterdam, The Netherlands., DeRosse P; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.; Hofstra North Shore - LIJ School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, USA., Knowles EE; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Glahn DC; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA., Djurovic S; NORMENT, KG Jebsen Centre, Oslo, Norway.; Oslo University Hospital, Oslo, Norway., Melle I; NORMENT, KG Jebsen Centre, Oslo, Norway.; Oslo University Hospital, Oslo, Norway.; University of Oslo, Oslo, Norway., Andreassen OA; NORMENT, KG Jebsen Centre, Oslo, Norway.; Oslo University Hospital, Oslo, Norway.; University of Oslo, Oslo, Norway., Christoforou A; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Steen VM; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Hellard SL; K.G. Jebsen Centre for Psychosis Research, Dr. Einar Martens Research Group for Biological Psychiatry, Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Sundet K; NORMENT, KG Jebsen Centre, Oslo, Norway.; Department of Psychology, University of Oslo, Oslo, Norway., Reinvang I; Department of Psychology, University of Oslo, Oslo, Norway., Espeseth T; Department of Psychology, University of Oslo, Oslo, Norway.; Norwegian Center for Mental Disorders Research, KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway., Lundervold AJ; K.G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway.; Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway.; Kavli Research Centre for Aging and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway., Giegling I; Department of Psychiatry, University of Halle, Halle, Germany., Konte B; Department of Psychiatry, University of Halle, Halle, Germany., Hartmann AM; Department of Psychiatry, University of Halle, Halle, Germany., Rujescu D; Department of Psychiatry, University of Halle, Halle, Germany., Roussos P; Department of Psychiatry, Friedman Brain Institute, Department of Genetics and Genomic Sciences, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; James J. Peters VA Medical Center, Mental Illness Research Education and Clinical Center (MIRECC), Bronx, NY, USA., Giakoumaki S; Department of Psychology, University of Crete, Rethymno, Crete, Greece., Burdick KE; Department of Psychiatry, Friedman Brain Institute, Department of Genetics and Genomic Sciences, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bitsios P; Department of Psychiatry, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.; Computational Medicine Laboratory, Institute of Computer Science at FORTH, Heraklion, Greece., Donohoe G; School of Psychology, National University of Ireland Galway, Galway, Ireland., Corley RP; Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO, USA., Visscher PM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Queensland Institute of Medical Research Berghofer, Brisbane, QLD, Australia.; Queensland Brain Institute, The University of Queensland, Brisbane, QLD, Australia.; University of Queensland Diamantina Institute, The University of Queensland, Princess Alexandra Hospital, Brisbane, QLD, Australia., Pendleton N; Centre for Integrated Genomic Medical Research, Institute of Population Health, University of Manchester, Manchester, UK., Malhotra AK; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.; Hofstra North Shore - LIJ School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, USA., Neale BM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Stanley Center for Psychiatric Genetics, Broad Institute of Harvard and MIT, Cambridge Center, Cambridge, MA, USA., Lencz T; Division of Psychiatry Research, Zucker Hillside Hospital, Glen Oaks, NY, USA.; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA.; Hofstra North Shore - LIJ School of Medicine, Departments of Psychiatry and Molecular Medicine, Hempstead, NY, USA., Keller MC; Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO, USA.; Department of Psychology, University of Colorado at Boulder, Boulder, CO, USA.
Source: Molecular psychiatry [Mol Psychiatry] 2016 Jun; Vol. 21 (6), pp. 837-43. Date of Electronic Publication: 2015 Sep 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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          Identifiers:
            – Type: issn-electronic
              Value: 1476-5578
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 6
          Titles:
            – TitleFull: Molecular psychiatry
              Type: main
ResultId 1