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Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.

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Title: Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.
Authors: Schiavon G; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Hrebien S; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Garcia-Murillas I; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Cutts RJ; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Pearson A; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Tarazona N; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Fenwick K; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Kozarewa I; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Lopez-Knowles E; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Ribas R; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Nerurkar A; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Osin P; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Chandarlapaty S; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Martin LA; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Dowsett M; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Smith IE; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK., Turner NC; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK. nicholas.turner@icr.ac.uk.
Source: Science translational medicine [Sci Transl Med] 2015 Nov 11; Vol. 7 (313), pp. 313ra182.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Schiavon+G%22">Schiavon G</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Hrebien+S%22">Hrebien S</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Garcia-Murillas+I%22">Garcia-Murillas I</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Cutts+RJ%22">Cutts RJ</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Pearson+A%22">Pearson A</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Tarazona+N%22">Tarazona N</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Fenwick+K%22">Fenwick K</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Kozarewa+I%22">Kozarewa I</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Lopez-Knowles+E%22">Lopez-Knowles E</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Ribas+R%22">Ribas R</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Nerurkar+A%22">Nerurkar A</searchLink>; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Osin+P%22">Osin P</searchLink>; Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Chandarlapaty+S%22">Chandarlapaty S</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Martin+LA%22">Martin LA</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK.<br /><searchLink fieldCode="AU" term="%22Dowsett+M%22">Dowsett M</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Smith+IE%22">Smith IE</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.<br /><searchLink fieldCode="AU" term="%22Turner+NC%22">Turner NC</searchLink>; The Breast Cancer Now Research Centre, The Institute of Cancer Research, London SW3 6JB, UK. Breast Unit, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK. nicholas.turner@icr.ac.uk.
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