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Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.

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Title: Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.
Authors: Bunda S; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada., Burrell K; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada., Heir P; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada., Zeng L; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, 635 Barnhill Drive, Indianapolis, Indiana 46202, USA., Alamsahebpour A; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada., Kano Y; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.; Department of Biochemistry, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada., Raught B; Princess Margaret Cancer Centre, Toronto Medical Discovery Tower, 9-701A, 101 College Street, Toronto, M5G1L7 Ontario, Canada., Zhang ZY; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, 635 Barnhill Drive, Indianapolis, Indiana 46202, USA., Zadeh G; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada., Ohh M; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.; Department of Biochemistry, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.
Source: Nature communications [Nat Commun] 2015 Nov 30; Vol. 6, pp. 8859. Date of Electronic Publication: 2015 Nov 30.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Bunda+S%22">Bunda S</searchLink>; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Burrell+K%22">Burrell K</searchLink>; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Heir+P%22">Heir P</searchLink>; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zeng+L%22">Zeng L</searchLink>; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, 635 Barnhill Drive, Indianapolis, Indiana 46202, USA.<br /><searchLink fieldCode="AU" term="%22Alamsahebpour+A%22">Alamsahebpour A</searchLink>; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Kano+Y%22">Kano Y</searchLink>; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.; Department of Biochemistry, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Raught+B%22">Raught B</searchLink>; Princess Margaret Cancer Centre, Toronto Medical Discovery Tower, 9-701A, 101 College Street, Toronto, M5G1L7 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+ZY%22">Zhang ZY</searchLink>; Department of Biochemistry and Molecular Biology, School of Medicine, Indiana University, 635 Barnhill Drive, Indianapolis, Indiana 46202, USA.<br /><searchLink fieldCode="AU" term="%22Zadeh+G%22">Zadeh G</searchLink>; Brain Tumour Research Centre, Hospital for Sick Children, University Health Network, Toronto Medical Discovery Tower, 101 College Street, East Tower, Toronto, M5G1L7 Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ohh+M%22">Ohh M</searchLink>; Department of Laboratory Medicine and Pathobiology, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.; Department of Biochemistry, University of Toronto, 1 King's College Circle, Toronto, M5S1A8 Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2015 Nov 30; Vol. 6, pp. 8859. <i>Date of Electronic Publication: </i>2015 Nov 30.
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