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Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.

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Title: Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
Authors: Burak MF; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Inouye KE; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., White A; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Lee A; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Tuncman G; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Calay ES; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Sekiya M; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Tirosh A; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Eguchi K; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Birrane G; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Lightwood D; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Howells L; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Odede G; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Hailu H; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., West S; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Garlish R; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Neale H; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Doyle C; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Moore A; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK., Hotamisligil GS; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. ghotamis@hsph.harvard.edu.
Source: Science translational medicine [Sci Transl Med] 2015 Dec 23; Vol. 7 (319), pp. 319ra205. Date of Electronic Publication: 2015 Dec 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Burak+MF%22">Burak MF</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Inouye+KE%22">Inouye KE</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22White+A%22">White A</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Lee+A%22">Lee A</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Tuncman+G%22">Tuncman G</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Calay+ES%22">Calay ES</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Sekiya+M%22">Sekiya M</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Tirosh+A%22">Tirosh A</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Eguchi+K%22">Eguchi K</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Birrane+G%22">Birrane G</searchLink>; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Lightwood+D%22">Lightwood D</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Howells+L%22">Howells L</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Odede+G%22">Odede G</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Hailu+H%22">Hailu H</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22West+S%22">West S</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Garlish+R%22">Garlish R</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Neale+H%22">Neale H</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Doyle+C%22">Doyle C</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Moore+A%22">Moore A</searchLink>; UCB (Union Chimique Belge), 208 Bath Road, Slough, Berkshire SL1 3WE, UK.<br /><searchLink fieldCode="AU" term="%22Hotamisligil+GS%22">Hotamisligil GS</searchLink>; Department of Genetics and Complex Diseases and Sabri Ülker Center, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. ghotamis@hsph.harvard.edu.
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