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An accessible pharmacodynamic transcriptional biomarker for notch target engagement.

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Title: An accessible pharmacodynamic transcriptional biomarker for notch target engagement.
Authors: Tanis KQ; Merck & Co., Kenilworth, New Jersey, USA., Podtelezhnikov AA; Merck & Co., Kenilworth, New Jersey, USA., Blackman SC; Merck & Co., Kenilworth, New Jersey, USA., Hing J; Merck & Co., Kenilworth, New Jersey, USA., Railkar RA; Merck & Co., Kenilworth, New Jersey, USA., Lunceford J; Merck & Co., Kenilworth, New Jersey, USA., Klappenbach JA; Merck & Co., Kenilworth, New Jersey, USA., Wei B; Merck & Co., Kenilworth, New Jersey, USA., Harman A; Merck & Co., Kenilworth, New Jersey, USA., Camargo LM; Merck & Co., Kenilworth, New Jersey, USA., Shah S; Merck & Co., Kenilworth, New Jersey, USA., Finney EM; Merck & Co., Kenilworth, New Jersey, USA., Hardwick JS; Merck & Co., Kenilworth, New Jersey, USA., Loboda A; Merck & Co., Kenilworth, New Jersey, USA., Watters J; Merck & Co., Kenilworth, New Jersey, USA., Bergstrom DA; Merck & Co., Kenilworth, New Jersey, USA., Demuth T; Merck & Co., Kenilworth, New Jersey, USA., Herman GA; Merck & Co., Kenilworth, New Jersey, USA., Strack PR; Merck & Co., Kenilworth, New Jersey, USA., Iannone R; Merck & Co., Kenilworth, New Jersey, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2016 Apr; Vol. 99 (4), pp. 370-80. Date of Electronic Publication: 2016 Feb 17.
Publication Type: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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