X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.

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Title: X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
Authors: Parsonage D; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Sheng F; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Hirata K; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA; Department of Pathology, University of California San Diego, La Jolla, CA, USA., Debnath A; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., McKerrow JH; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Reed SL; Department of Pathology, University of California San Diego, La Jolla, CA, USA; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Abagyan R; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Poole LB; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Podust LM; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. Electronic address: lpodust@ucsd.edu.
Source: Journal of structural biology [J Struct Biol] 2016 May; Vol. 194 (2), pp. 180-90. Date of Electronic Publication: 2016 Feb 12.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9011206 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8657 (Electronic) Linking ISSN: 10478477 NLM ISO Abbreviation: J Struct Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: X-ray structures of thioredoxin and thioredoxin reductase from Entamoeba histolytica and prevailing hypothesis of the mechanism of Auranofin action.
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  Data: <searchLink fieldCode="AU" term="%22Parsonage+D%22">Parsonage D</searchLink>; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Sheng+F%22">Sheng F</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hirata+K%22">Hirata K</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA; Department of Pathology, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Debnath+A%22">Debnath A</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22McKerrow+JH%22">McKerrow JH</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reed+SL%22">Reed SL</searchLink>; Department of Pathology, University of California San Diego, La Jolla, CA, USA; Department of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Abagyan+R%22">Abagyan R</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Poole+LB%22">Poole LB</searchLink>; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Podust+LM%22">Podust LM</searchLink>; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA. Electronic address: lpodust@ucsd.edu.
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  Data: <searchLink fieldCode="JN" term="%229011206%22">Journal of structural biology</searchLink> [J Struct Biol] 2016 May; Vol. 194 (2), pp. 180-90. <i>Date of Electronic Publication: </i>2016 Feb 12.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9011206 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-8657 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210478477%22">10478477 </searchLink><i>NLM ISO Abbreviation: </i>J Struct Biol <i>Subsets: </i>MEDLINE
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              Text: 2016 May
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