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Testing the role of predicted gene knockouts in human anthropometric trait variation.

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Title: Testing the role of predicted gene knockouts in human anthropometric trait variation.
Authors: Lessard S; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada Faculté de Médecine, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Manning AK; Medical and Population Genetics Program, Broad Institute, Cambridge, MA 02142, USA Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA 02114, USA Department of Medicine and., Low-Kam C; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada Faculté de Médecine, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Auer PL; School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI 53201-0413, USA., Giri A; Division of Epidemiology, Institute for Medicine and Public Health and., Graff M; University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27599, USA., Schurmann C; The Charles Bronfman Institute for Personalized Medicine and The Mindich Child Health and Development Institute, the Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, UK., Luan J; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Esko T; Medical and Population Genetics Program, Broad Institute, Cambridge, MA 02142, USA Estonian Genome Center, University of Tartu, Tartu, Estonia Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Children's Hospital Boston, Boston, MA 02115, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine and., Lu Y; The Charles Bronfman Institute for Personalized Medicine and., Carlson C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA., Caulfield M; Clinical Pharmacology, William Harvey Research Institute and NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Dubé MP; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada Faculté de Médecine, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Jackson RD; Division of Endocrinology, Diabetes and Metabolism, Ohio State University, Columbus, OH 43210, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA., McKnight B; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Mongrain I; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA., Rhainds D; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada., Sotoodehnia N; Division of Cardiology, Cardiovascular Health Research Unit, University of Washington, Seattle, WA 98195-6422, USA., Hirschhorn JN; Medical and Population Genetics Program, Broad Institute, Cambridge, MA 02142, USA Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology, Genetics and Basic and Translational Obesity Research, Children's Hospital Boston, Boston, MA 02115, USA., Scott RA; Medical Research Council Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Munroe PB; Clinical Pharmacology, William Harvey Research Institute and NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter EX2 5DW, UK., Loos RJ; The Charles Bronfman Institute for Personalized Medicine and The Mindich Child Health and Development Institute, the Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., North KE; University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27599, USA., Edwards TL; Division of Epidemiology, Institute for Medicine and Public Health and Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN 37203, USA., Tardif JC; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada Faculté de Médecine, Université de Montréal, Montréal, Québec H3T 1J4, Canada., Lindgren CM; Medical and Population Genetics Program, Broad Institute, Cambridge, MA 02142, USA Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK The Big Data Institute, University of Oxford, Oxford, UK., Lettre G; Montreal Heart Institute, Montréal, Québec H1T 1C8, Canada Faculté de Médecine, Université de Montréal, Montréal, Québec H3T 1J4, Canada guillaume.lettre@umontreal.ca.
Corporate Authors: NHLBI GO Exome Sequence Project, GOT2D, T2D-GENES, GIANT Consortium
Source: Human molecular genetics [Hum Mol Genet] 2016 May 15; Vol. 25 (10), pp. 2082-2092. Date of Electronic Publication: 2016 Feb 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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