4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
Saved in:
| Title: | 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling. |
|---|---|
| Authors: | Trist IM; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Nannetti G; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Tintori C; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Fallacara AL; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Deodato D; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Mercorelli B; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Palù G; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Wijtmans M; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Gospodova T; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria., Edink E; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Verheij M; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., de Esch I; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Viteva L; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria., Loregian A; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Botta M; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.; Sbarro Institute for Cancer Research and Molecular Medicine, Temple University , BioLife Science Building, Suite 333, 1900 N 12th Street, Philadelphia, Pennsylvania 19122, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2016 Mar 24; Vol. 59 (6), pp. 2688-703. Date of Electronic Publication: 2016 Mar 11. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 26924568 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Trist+IM%22">Trist IM</searchLink>; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Nannetti+G%22">Nannetti G</searchLink>; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Tintori+C%22">Tintori C</searchLink>; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Fallacara+AL%22">Fallacara AL</searchLink>; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Deodato+D%22">Deodato D</searchLink>; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Mercorelli+B%22">Mercorelli B</searchLink>; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Palù+G%22">Palù G</searchLink>; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Wijtmans+M%22">Wijtmans M</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gospodova+T%22">Gospodova T</searchLink>; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Edink+E%22">Edink E</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verheij+M%22">Verheij M</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Esch+I%22">de Esch I</searchLink>; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Viteva+L%22">Viteva L</searchLink>; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria.<br /><searchLink fieldCode="AU" term="%22Loregian+A%22">Loregian A</searchLink>; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Botta+M%22">Botta M</searchLink>; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.; Sbarro Institute for Cancer Research and Molecular Medicine, Temple University , BioLife Science Building, Suite 333, 1900 N 12th Street, Philadelphia, Pennsylvania 19122, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2016 Mar 24; Vol. 59 (6), pp. 2688-703. <i>Date of Electronic Publication: </i>2016 Mar 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=26924568 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.5b01935 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2688 Titles: – TitleFull: 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Trist IM – PersonEntity: Name: NameFull: Nannetti G – PersonEntity: Name: NameFull: Tintori C – PersonEntity: Name: NameFull: Fallacara AL – PersonEntity: Name: NameFull: Deodato D – PersonEntity: Name: NameFull: Mercorelli B – PersonEntity: Name: NameFull: Palù G – PersonEntity: Name: NameFull: Wijtmans M – PersonEntity: Name: NameFull: Gospodova T – PersonEntity: Name: NameFull: Edink E – PersonEntity: Name: NameFull: Verheij M – PersonEntity: Name: NameFull: de Esch I – PersonEntity: Name: NameFull: Viteva L – PersonEntity: Name: NameFull: Loregian A – PersonEntity: Name: NameFull: Botta M IsPartOfRelationships: – BibEntity: Dates: – D: 24 M: 03 Text: 2016 Mar 24 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 59 – Type: issue Value: 6 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
| ResultId | 1 |
