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Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.

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Title: Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.
Authors: Uphoff S; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK. Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. stephan.uphoff@bioch.ox.ac.uk johan_paulsson@harvard.edu., Lord ND; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA., Okumus B; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA., Potvin-Trottier L; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Biophysics Ph.D. Program, Harvard Medical School, USA., Sherratt DJ; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK., Paulsson J; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. stephan.uphoff@bioch.ox.ac.uk johan_paulsson@harvard.edu.
Source: Science (New York, N.Y.) [Science] 2016 Mar 04; Vol. 351 (6277), pp. 1094-7.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Uphoff+S%22">Uphoff S</searchLink>; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK. Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. stephan.uphoff@bioch.ox.ac.uk johan_paulsson@harvard.edu.<br /><searchLink fieldCode="AU" term="%22Lord+ND%22">Lord ND</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Okumus+B%22">Okumus B</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Potvin-Trottier+L%22">Potvin-Trottier L</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Biophysics Ph.D. Program, Harvard Medical School, USA.<br /><searchLink fieldCode="AU" term="%22Sherratt+DJ%22">Sherratt DJ</searchLink>; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.<br /><searchLink fieldCode="AU" term="%22Paulsson+J%22">Paulsson J</searchLink>; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. stephan.uphoff@bioch.ox.ac.uk johan_paulsson@harvard.edu.
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