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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.

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Title: Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.
Authors: Zanoni P; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Khetarpal SA; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Larach DB; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Hancock-Cerutti WF; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. INSERM UMR 1166 ICAN, Université Pierre et Marie Curie Paris 6, Hôpital de la Pitié, Paris, France., Millar JS; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Cuchel M; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., DerOhannessian S; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Kontush A; INSERM UMR 1166 ICAN, Université Pierre et Marie Curie Paris 6, Hôpital de la Pitié, Paris, France., Surendran P; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Saleheen D; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Centre for Non-Communicable Diseases, Karachi, Pakistan., Trompet S; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands. Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands. The Interuniversity Cardiology Institute of the Netherlands, Utrecht, Netherlands., De Craen A; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands., Deloukas P; Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Sattar N; Institute of Cardiovascular and Medical Sciences, British Heart Foundation, Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Packard C; Glasgow Clinical Research Facility, Western Infirmary, Glasgow, UK., Majumder Aa; National Institute of Cardiovascular Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh., Alam DS; International Centre for Diarrhoeal Disease Research, Mohakhali, Dhaka, Bangladesh., Di Angelantonio E; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Abecasis G; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA., Chowdhury R; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Erdmann J; Institute for Integrative and Experimental Genomics, University of Lübeck, Lübeck 23562, Germany., Nordestgaard BG; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark., Nielsen SF; Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, Herlev, Denmark., Tybjærg-Hansen A; Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark., Schmidt RF; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospitals, Copenhagen, Denmark., Kuulasmaa K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Liu DJ; Department of Public Health Sciences, College of Medicine, Pennsylvania State University, Hershey, PA 17033, USA., Perola M; Department of Health, National Institute for Health and Welfare, Helsinki, Finland. Institute of Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland., Blankenberg S; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg, Germany. University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Salomaa V; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Männistö S; Department of Health, National Institute for Health and Welfare, Helsinki, Finland., Amouyel P; Department of Epidemiology and Public Health, Institut Pasteur de Lille, Lille, France., Arveiler D; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France., Ferrieres J; Department of Epidemiology, Toulouse University-CHU Toulouse, Toulouse, France., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany. Department of Medicine I, Ludwig-Maximilians-University Munich, Munich, Germany., Ferrario M; Research Centre in Epidemiology and Preventive Medicine, Department of Clinical and Experimental Medicine, University of Insubria, Varese, Italy., Kee F; UKCRC Centre of Excellence for Public Health, Queens University, Belfast, Northern Ireland., Willer CJ; Department of Computational Medicine and Bioinformatics, Department of Human Genetics, and Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Samani N; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK. National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, Glenfield Hotel, Leicester, UK., Schunkert H; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany., Butterworth AS; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Howson JM; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Peloso GM; Broad Institute and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA., Stitziel NO; Department of Medicine, Division of Cardiology, Department of Genetics, and the McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110, USA., Danesh J; Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK. Wellcome Trust Sanger Institute, Genome Campus, Hinxton, UK., Kathiresan S; Broad Institute and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA., Rader DJ; Departments of Genetics and Medicine, Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. rader@mail.med.upenn.edu.
Corporate Authors: CHD Exome+ Consortium, CARDIoGRAM Exome Consortium, Global Lipids Genetics Consortium
Source: Science (New York, N.Y.) [Science] 2016 Mar 11; Vol. 351 (6278), pp. 1166-71.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
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  Data: Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.
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            – Type: volume
              Value: 351
            – Type: issue
              Value: 6278
          Titles:
            – TitleFull: Science (New York, N.Y.)
              Type: main
ResultId 1