Nucleosomes impede Cas9 access to DNA in vivo and in vitro.
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| Title: | Nucleosomes impede Cas9 access to DNA in vivo and in vitro. |
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| Authors: | Horlbeck MA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Witkowsky LB; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Guglielmi B; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Replogle JM; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Gilbert LA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Villalta JE; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States., Torigoe SE; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Tjian R; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, United States.; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; CIRM Center of Excellence, University of California, Berkeley, Berkeley, United States., Weissman JS; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, United States.; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, United States.; Center for RNA Systems Biology, University of California, San Francisco, San Francisco, United States. |
| Source: | ELife [Elife] 2016 Mar 17; Vol. 5. Date of Electronic Publication: 2016 Mar 17. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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