Integrating computational and chemical biology tools in the discovery of antiangiogenic small molecule ligands of FGF2 derived from endogenous inhibitors.

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Title: Integrating computational and chemical biology tools in the discovery of antiangiogenic small molecule ligands of FGF2 derived from endogenous inhibitors.
Authors: Foglieni C; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy., Pagano K; Laboratorio NMR, Istituto per lo Studio delle Macromolecole, Consiglio Nazionale delle Ricerche, Milano, 20133 Italy., Lessi M; Dipartimento di Chimica e Chimica Industriale, Università Di Pisa, Pisa, 56124, Italy., Bugatti A; Section of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, 25123 Italy., Moroni E; Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, 20131 Italy., Pinessi D; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy., Resovi A; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy., Ribatti D; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, 70121 Italy, and National Cancer Institute 'Giovanni Paolo II', Bari, 70124 Italy., Bertini S; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Milano 20133, Italy., Ragona L; Laboratorio NMR, Istituto per lo Studio delle Macromolecole, Consiglio Nazionale delle Ricerche, Milano, 20133 Italy., Bellina F; Dipartimento di Chimica e Chimica Industriale, Università Di Pisa, Pisa, 56124, Italy., Rusnati M; Section of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, 25123 Italy., Colombo G; Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, 20131 Italy., Taraboletti G; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy.
Source: Scientific reports [Sci Rep] 2016 Mar 22; Vol. 6, pp. 23432. Date of Electronic Publication: 2016 Mar 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Foglieni+C%22">Foglieni C</searchLink>; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy.<br /><searchLink fieldCode="AU" term="%22Pagano+K%22">Pagano K</searchLink>; Laboratorio NMR, Istituto per lo Studio delle Macromolecole, Consiglio Nazionale delle Ricerche, Milano, 20133 Italy.<br /><searchLink fieldCode="AU" term="%22Lessi+M%22">Lessi M</searchLink>; Dipartimento di Chimica e Chimica Industriale, Università Di Pisa, Pisa, 56124, Italy.<br /><searchLink fieldCode="AU" term="%22Bugatti+A%22">Bugatti A</searchLink>; Section of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, 25123 Italy.<br /><searchLink fieldCode="AU" term="%22Moroni+E%22">Moroni E</searchLink>; Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, 20131 Italy.<br /><searchLink fieldCode="AU" term="%22Pinessi+D%22">Pinessi D</searchLink>; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy.<br /><searchLink fieldCode="AU" term="%22Resovi+A%22">Resovi A</searchLink>; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy.<br /><searchLink fieldCode="AU" term="%22Ribatti+D%22">Ribatti D</searchLink>; Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, 70121 Italy, and National Cancer Institute 'Giovanni Paolo II', Bari, 70124 Italy.<br /><searchLink fieldCode="AU" term="%22Bertini+S%22">Bertini S</searchLink>; Istituto di Ricerche Chimiche e Biochimiche G. Ronzoni, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Ragona+L%22">Ragona L</searchLink>; Laboratorio NMR, Istituto per lo Studio delle Macromolecole, Consiglio Nazionale delle Ricerche, Milano, 20133 Italy.<br /><searchLink fieldCode="AU" term="%22Bellina+F%22">Bellina F</searchLink>; Dipartimento di Chimica e Chimica Industriale, Università Di Pisa, Pisa, 56124, Italy.<br /><searchLink fieldCode="AU" term="%22Rusnati+M%22">Rusnati M</searchLink>; Section of Experimental Oncology and Immunology, Department of Molecular and Translational Medicine, University of Brescia, Brescia, 25123 Italy.<br /><searchLink fieldCode="AU" term="%22Colombo+G%22">Colombo G</searchLink>; Istituto di Chimica del Riconoscimento Molecolare, Consiglio Nazionale delle Ricerche, Milano, 20131 Italy.<br /><searchLink fieldCode="AU" term="%22Taraboletti+G%22">Taraboletti G</searchLink>; Tumor Angiogenesis Unit, Department of Oncology, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, 24126 Italy.
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