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Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.

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Title: Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.
Authors: Nicoli ER; Department of Pharmacology, University of Oxford, Oxford, United Kingdom., Al Eisa N; Department of Pharmacology, University of Oxford, Oxford, United Kingdom., Cluzeau CV; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Wassif CA; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Gray J; Department of Pharmacology, University of Oxford, Oxford, United Kingdom., Burkert KR; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Smith DA; Department of Pharmacology, University of Oxford, Oxford, United Kingdom., Morris L; Department of Pharmacology, University of Oxford, Oxford, United Kingdom., Cologna SM; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Peer CJ; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America., Sissung TM; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America., Uscatu CD; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.; Department of Cellular and Molecular Biology, University of Medicine and Pharmacy of Craiova, Craiova, Romania., Figg WD; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America., Pavan WJ; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Vite CH; School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America., Porter FD; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America., Platt FM; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
Source: PloS one [PLoS One] 2016 Mar 28; Vol. 11 (3), pp. e0152007. Date of Electronic Publication: 2016 Mar 28 (Print Publication: 2016).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
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  Data: Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.
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  Data: <searchLink fieldCode="AU" term="%22Nicoli+ER%22">Nicoli ER</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Al+Eisa+N%22">Al Eisa N</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cluzeau+CV%22">Cluzeau CV</searchLink>; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Wassif+CA%22">Wassif CA</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Gray+J%22">Gray J</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Burkert+KR%22">Burkert KR</searchLink>; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+DA%22">Smith DA</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Morris+L%22">Morris L</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cologna+SM%22">Cologna SM</searchLink>; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Peer+CJ%22">Peer CJ</searchLink>; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Sissung+TM%22">Sissung TM</searchLink>; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Uscatu+CD%22">Uscatu CD</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.; Department of Cellular and Molecular Biology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.<br /><searchLink fieldCode="AU" term="%22Figg+WD%22">Figg WD</searchLink>; Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Pavan+WJ%22">Pavan WJ</searchLink>; Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Vite+CH%22">Vite CH</searchLink>; School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.<br /><searchLink fieldCode="AU" term="%22Porter+FD%22">Porter FD</searchLink>; Section of Molecular Dysmorphology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Platt+FM%22">Platt FM</searchLink>; Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
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