A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.

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Title: A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.
Authors: Leslie EJ; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Carlson JC; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Biostatistics., Shaffer JR; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Feingold E; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Biostatistics.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Wehby G; Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa City, IA 52246, USA., Laurie CA; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Jain D; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Laurie CC; Department of Biostatistics, Genetic Coordinating Center, University of Washington, Seattle, WA 98195, USA., Doheny KF; Center for Inherited Disease Research, Johns Hopkins University, Baltimore, MD 21224, USA., McHenry T; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Resick J; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Sanchez C; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Jacobs J; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Emanuele B; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Vieira AR; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Neiswanger K; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Lidral AC; Department of Orthodontics., Valencia-Ramirez LC; Fundación Clínica Noel, Medellin 050012, Colombia., Lopez-Palacio AM; Department of Basic Integrated Studies, College of Dentistry., Valencia DR; Population Genetics and Mutacarcinogenesis Group, University of Antioquia, Medellin 050001, Colombia., Arcos-Burgos M; Genomics and Predictive Medicine, Genome Biology Department, John Curtin School of Medical Research, ANU College of Medicine, Biology & Environment, The Australian National University, Canberra, ACT 0200, Australia., Czeizel AE; Foundation for the Community Control of Hereditary Diseases, Budapest 1051, Hungary., Field LL; Department of Medical Genetics, University of British Columbia, Vancouver V6H 3N1, Canada., Padilla CD; Department of Pediatrics, College of Medicine; and Institute of Human Genetics, National Institutes of Health; University of the Philippines Manila, Manilla, The Philippines 1000.; Philippine Genome Center, University of the Philippines System, Manilla, The Philippines 1101., Cutiongco-de la Paz EM; Department of Pediatrics, College of Medicine; and Institute of Human Genetics, National Institutes of Health; University of the Philippines Manila, Manilla, The Philippines 1000.; Philippine Genome Center, University of the Philippines System, Manilla, The Philippines 1101., Deleyiannis F; Department of Surgery, Plastic and Reconstructive Surgery, University of Colorado School of Medicine, Denver, CO 80045, USA., Christensen K; Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense DK-5230 Denmark., Munger RG; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT 84322, USA., Lie RT; Department of Global Public Health and Primary Care, University of Bergen, Bergen, NO-5020 Norway., Wilcox A; Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA., Romitti PA; Department of Epidemiology, College of Public Health., Castilla EE; CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina.; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics)., Mereb JC; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at Hospital de Area, El Bolson 8430, Argentina., Poletta FA; CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina.; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics)., Orioli IM; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics).; Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro 21941-617, Brazil., Carvalho FM; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics)., Hecht JT; Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Blanton SH; Dr. John T. Macdonald Foundation Department of Human Genetics, Hussman Institute for Human Genomics, Mailman School of Medicine, University of Miami, Miami, FL 33124, USA., Buxó CJ; School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico 00936., Butali A; Department of Oral Pathology, Radiology and Medicine, Dows Institute for Dental Research, College of Dentistry., Mossey PA; Department of Orthodontics, University of Dundee, Dundee DD1 4HN, Scotland., Adeyemo WL; Department of Oral and Maxillofacial Surgery. College of Medicine, University of Lagos, Lagos P.M.B. 12003, Nigeria., James O; Department of Oral and Maxillofacial Surgery. College of Medicine, University of Lagos, Lagos P.M.B. 12003, Nigeria., Braimah RO; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University, Ife-Ife P.M.B. 13, Nigeria., Aregbesola BS; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University, Ife-Ife P.M.B. 13, Nigeria., Eshete MA; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia., Abate F; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia., Koruyucu M; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey., Seymen F; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey., Ma L; Peking University, School of Stomatology, Beijing 100081, China., de Salamanca JE; Hospital Infantil Universitario Niño Jesús; Unidad de Cirugía Plástica, Madrid 28009, Spain., Weinberg SM; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA., Moreno L; Department of Orthodontics., Murray JC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Marazita ML; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA marazita@pitt.edu.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Clinical and Translational Science, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Source: Human molecular genetics [Hum Mol Genet] 2016 Jul 01; Vol. 25 (13), pp. 2862-2872. Date of Electronic Publication: 2016 Mar 30.
Publication Type: Journal Article
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
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  Data: A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.
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  Data: <searchLink fieldCode="AU" term="%22Leslie+EJ%22">Leslie EJ</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.<br /><searchLink fieldCode="AU" term="%22Carlson+JC%22">Carlson JC</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Biostatistics.<br /><searchLink fieldCode="AU" term="%22Shaffer+JR%22">Shaffer JR</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.<br /><searchLink fieldCode="AU" term="%22Feingold+E%22">Feingold E</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; 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Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.<br /><searchLink fieldCode="AU" term="%22Neiswanger+K%22">Neiswanger K</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.<br /><searchLink fieldCode="AU" term="%22Lidral+AC%22">Lidral AC</searchLink>; Department of Orthodontics.<br /><searchLink fieldCode="AU" term="%22Valencia-Ramirez+LC%22">Valencia-Ramirez LC</searchLink>; Fundación Clínica Noel, Medellin 050012, Colombia.<br /><searchLink fieldCode="AU" term="%22Lopez-Palacio+AM%22">Lopez-Palacio AM</searchLink>; Department of Basic Integrated Studies, College of Dentistry.<br /><searchLink fieldCode="AU" term="%22Valencia+DR%22">Valencia DR</searchLink>; 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Philippine Genome Center, University of the Philippines System, Manilla, The Philippines 1101.<br /><searchLink fieldCode="AU" term="%22Cutiongco-de+la+Paz+EM%22">Cutiongco-de la Paz EM</searchLink>; Department of Pediatrics, College of Medicine; and Institute of Human Genetics, National Institutes of Health; University of the Philippines Manila, Manilla, The Philippines 1000.; Philippine Genome Center, University of the Philippines System, Manilla, The Philippines 1101.<br /><searchLink fieldCode="AU" term="%22Deleyiannis+F%22">Deleyiannis F</searchLink>; Department of Surgery, Plastic and Reconstructive Surgery, University of Colorado School of Medicine, Denver, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Christensen+K%22">Christensen K</searchLink>; Department of Epidemiology, Institute of Public Health, University of Southern Denmark, Odense DK-5230 Denmark.<br /><searchLink fieldCode="AU" term="%22Munger+RG%22">Munger RG</searchLink>; Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT 84322, USA.<br /><searchLink fieldCode="AU" term="%22Lie+RT%22">Lie RT</searchLink>; 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CEMIC: Center for Medical Education and Clinical Research, Buenos Aires 1431, Argentina.; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics).<br /><searchLink fieldCode="AU" term="%22Orioli+IM%22">Orioli IM</searchLink>; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics).; Department of Genetics, Institute of Biology, Federal University of Rio de Janeiro, Rio de Janeiro 21941-617, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+FM%22">Carvalho FM</searchLink>; Laboratory of Congenital Malformation Epidemiology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro 21040-360, Brazil.; ECLAMC (Latin American Collaborative Study of Congenital Malformations) at INAGEMP (National Institute of Population Medical Genetics).<br /><searchLink fieldCode="AU" term="%22Hecht+JT%22">Hecht JT</searchLink>; Department of Pediatrics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Blanton+SH%22">Blanton SH</searchLink>; Dr. John T. Macdonald Foundation Department of Human Genetics, Hussman Institute for Human Genomics, Mailman School of Medicine, University of Miami, Miami, FL 33124, USA.<br /><searchLink fieldCode="AU" term="%22Buxó+CJ%22">Buxó CJ</searchLink>; School of Dental Medicine, University of Puerto Rico, San Juan, Puerto Rico 00936.<br /><searchLink fieldCode="AU" term="%22Butali+A%22">Butali A</searchLink>; Department of Oral Pathology, Radiology and Medicine, Dows Institute for Dental Research, College of Dentistry.<br /><searchLink fieldCode="AU" term="%22Mossey+PA%22">Mossey PA</searchLink>; Department of Orthodontics, University of Dundee, Dundee DD1 4HN, Scotland.<br /><searchLink fieldCode="AU" term="%22Adeyemo+WL%22">Adeyemo WL</searchLink>; Department of Oral and Maxillofacial Surgery. College of Medicine, University of Lagos, Lagos P.M.B. 12003, Nigeria.<br /><searchLink fieldCode="AU" term="%22James+O%22">James O</searchLink>; Department of Oral and Maxillofacial Surgery. College of Medicine, University of Lagos, Lagos P.M.B. 12003, Nigeria.<br /><searchLink fieldCode="AU" term="%22Braimah+RO%22">Braimah RO</searchLink>; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University, Ife-Ife P.M.B. 13, Nigeria.<br /><searchLink fieldCode="AU" term="%22Aregbesola+BS%22">Aregbesola BS</searchLink>; Department of Oral and Maxillofacial Surgery, Obafemi Awolowo University, Ife-Ife P.M.B. 13, Nigeria.<br /><searchLink fieldCode="AU" term="%22Eshete+MA%22">Eshete MA</searchLink>; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Abate+F%22">Abate F</searchLink>; Surgical Department, School of Medicine, Addis Ababa University, Addis Ababa, P.O. Box 26493, Ethiopia.<br /><searchLink fieldCode="AU" term="%22Koruyucu+M%22">Koruyucu M</searchLink>; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey.<br /><searchLink fieldCode="AU" term="%22Seymen+F%22">Seymen F</searchLink>; Department of Pedodontics, Istanbul University, Istanbul 34116, Turkey.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Peking University, School of Stomatology, Beijing 100081, China.<br /><searchLink fieldCode="AU" term="%22de+Salamanca+JE%22">de Salamanca JE</searchLink>; Hospital Infantil Universitario Niño Jesús; Unidad de Cirugía Plástica, Madrid 28009, Spain.<br /><searchLink fieldCode="AU" term="%22Weinberg+SM%22">Weinberg SM</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA.<br /><searchLink fieldCode="AU" term="%22Moreno+L%22">Moreno L</searchLink>; Department of Orthodontics.<br /><searchLink fieldCode="AU" term="%22Murray+JC%22">Murray JC</searchLink>; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.<br /><searchLink fieldCode="AU" term="%22Marazita+ML%22">Marazita ML</searchLink>; Department of Oral Biology, Center for Craniofacial and Dental Genetics, School of Dental Medicine, University of Pittsburgh, Pittsburgh, PA 15219, USA marazita@pitt.edu.; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.; Clinical and Translational Science, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
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  Data: <searchLink fieldCode="JN" term="%229208958%22">Human molecular genetics</searchLink> [Hum Mol Genet] 2016 Jul 01; Vol. 25 (13), pp. 2862-2872. <i>Date of Electronic Publication: </i>2016 Mar 30.
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      – TitleFull: A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13.
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            NameFull: Carvalho FM
      – PersonEntity:
          Name:
            NameFull: Hecht JT
      – PersonEntity:
          Name:
            NameFull: Blanton SH
      – PersonEntity:
          Name:
            NameFull: Buxó CJ
      – PersonEntity:
          Name:
            NameFull: Butali A
      – PersonEntity:
          Name:
            NameFull: Mossey PA
      – PersonEntity:
          Name:
            NameFull: Adeyemo WL
      – PersonEntity:
          Name:
            NameFull: James O
      – PersonEntity:
          Name:
            NameFull: Braimah RO
      – PersonEntity:
          Name:
            NameFull: Aregbesola BS
      – PersonEntity:
          Name:
            NameFull: Eshete MA
      – PersonEntity:
          Name:
            NameFull: Abate F
      – PersonEntity:
          Name:
            NameFull: Koruyucu M
      – PersonEntity:
          Name:
            NameFull: Seymen F
      – PersonEntity:
          Name:
            NameFull: Ma L
      – PersonEntity:
          Name:
            NameFull: de Salamanca JE
      – PersonEntity:
          Name:
            NameFull: Weinberg SM
      – PersonEntity:
          Name:
            NameFull: Moreno L
      – PersonEntity:
          Name:
            NameFull: Murray JC
      – PersonEntity:
          Name:
            NameFull: Marazita ML
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: 2016 Jul 01
              Type: published
              Y: 2016
          Identifiers:
            – Type: issn-electronic
              Value: 1460-2083
          Numbering:
            – Type: volume
              Value: 25
            – Type: issue
              Value: 13
          Titles:
            – TitleFull: Human molecular genetics
              Type: main
ResultId 1