Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.
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| Title: | Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. |
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| Authors: | Zou MF, Keck TM, Kumar V, Donthamsetti P; Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons , New York, New York 10027, United States.; Division of Molecular Therapeutics, New York State Psychiatric Institute , New York, New York 10032, United States., Michino M, Burzynski C, Schweppe C, Bonifazi A, Free RB; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health , 5625 Fishers Lane, Room 4S-04, Bethesda, Maryland 20892-9405, United States., Sibley DR; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health , 5625 Fishers Lane, Room 4S-04, Bethesda, Maryland 20892-9405, United States., Janowsky A; Research & Development Service, Veterans Affairs Portland Health Care System , Portland, Oregon 97239, United States.; Department of Psychiatry and Behavioral Neuroscience, School of Medicine and Methamphetamine Abuse Research Center, Oregon Health & Science University , Portland, Oregon 97239, United States., Shi L; Department of Physiology and Biophysics and the Institute for Computational Biomedicine, Weill Medical College of Cornell University , New York, New York 10065, United States., Javitch JA; Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons , New York, New York 10027, United States.; Division of Molecular Therapeutics, New York State Psychiatric Institute , New York, New York 10032, United States., Newman AH |
| Source: | Journal of medicinal chemistry [J Med Chem] 2016 Apr 14; Vol. 59 (7), pp. 2973-88. Date of Electronic Publication: 2016 Apr 01. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 27035329 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zou+MF%22">Zou MF</searchLink><br /><searchLink fieldCode="AU" term="%22Keck+TM%22">Keck TM</searchLink><br /><searchLink fieldCode="AU" term="%22Kumar+V%22">Kumar V</searchLink><br /><searchLink fieldCode="AU" term="%22Donthamsetti+P%22">Donthamsetti P</searchLink>; Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons , New York, New York 10027, United States.; Division of Molecular Therapeutics, New York State Psychiatric Institute , New York, New York 10032, United States.<br /><searchLink fieldCode="AU" term="%22Michino+M%22">Michino M</searchLink><br /><searchLink fieldCode="AU" term="%22Burzynski+C%22">Burzynski C</searchLink><br /><searchLink fieldCode="AU" term="%22Schweppe+C%22">Schweppe C</searchLink><br /><searchLink fieldCode="AU" term="%22Bonifazi+A%22">Bonifazi A</searchLink><br /><searchLink fieldCode="AU" term="%22Free+RB%22">Free RB</searchLink>; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health , 5625 Fishers Lane, Room 4S-04, Bethesda, Maryland 20892-9405, United States.<br /><searchLink fieldCode="AU" term="%22Sibley+DR%22">Sibley DR</searchLink>; Molecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health , 5625 Fishers Lane, Room 4S-04, Bethesda, Maryland 20892-9405, United States.<br /><searchLink fieldCode="AU" term="%22Janowsky+A%22">Janowsky A</searchLink>; Research & Development Service, Veterans Affairs Portland Health Care System , Portland, Oregon 97239, United States.; Department of Psychiatry and Behavioral Neuroscience, School of Medicine and Methamphetamine Abuse Research Center, Oregon Health & Science University , Portland, Oregon 97239, United States.<br /><searchLink fieldCode="AU" term="%22Shi+L%22">Shi L</searchLink>; Department of Physiology and Biophysics and the Institute for Computational Biomedicine, Weill Medical College of Cornell University , New York, New York 10065, United States.<br /><searchLink fieldCode="AU" term="%22Javitch+JA%22">Javitch JA</searchLink>; Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons , New York, New York 10027, United States.; Division of Molecular Therapeutics, New York State Psychiatric Institute , New York, New York 10032, United States.<br /><searchLink fieldCode="AU" term="%22Newman+AH%22">Newman AH</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2016 Apr 14; Vol. 59 (7), pp. 2973-88. <i>Date of Electronic Publication: </i>2016 Apr 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=27035329 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.5b01612 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2973 Titles: – TitleFull: Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zou MF – PersonEntity: Name: NameFull: Keck TM – PersonEntity: Name: NameFull: Kumar V – PersonEntity: Name: NameFull: Donthamsetti P – PersonEntity: Name: NameFull: Michino M – PersonEntity: Name: NameFull: Burzynski C – PersonEntity: Name: NameFull: Schweppe C – PersonEntity: Name: NameFull: Bonifazi A – PersonEntity: Name: NameFull: Free RB – PersonEntity: Name: NameFull: Sibley DR – PersonEntity: Name: NameFull: Janowsky A – PersonEntity: Name: NameFull: Shi L – PersonEntity: Name: NameFull: Javitch JA – PersonEntity: Name: NameFull: Newman AH IsPartOfRelationships: – BibEntity: Dates: – D: 14 M: 04 Text: 2016 Apr 14 Type: published Y: 2016 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 59 – Type: issue Value: 7 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
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