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Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.

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Title: Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.
Authors: Zimmer S; Medizinische Klinik und Poliklinik II, University Hospital Bonn, 53105 Bonn, Germany., Grebe A; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany., Bakke SS; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway., Bode N; Medizinische Klinik und Poliklinik II, University Hospital Bonn, 53105 Bonn, Germany., Halvorsen B; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0424 Oslo, Norway., Ulas T; Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany., Skjelland M; Department of Neurology, Oslo University Hospital Rikshospitalet, 0424 Oslo, Norway., De Nardo D; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia. Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia., Labzin LI; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany., Kerksiek A; Institute of Clinical Chemistry und Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany., Hempel C; Addi and Cassi Fund, Reno, NV 89511, USA., Heneka MT; Clinic and Polyclinic for Neurology, University Hospital Bonn, 53105 Bonn, Germany., Hawxhurst V; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Boston, MA 02114, USA., Fitzgerald ML; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Boston, MA 02114, USA., Trebicka J; Medizinische Klinik und Poliklinik I, University Hospital Bonn, 53105 Bonn, Germany. Faculty of Health Sciences, University of Southern Denmark Campusvej 55, DK-5230 Odense M, Denmark., Björkhem I; Division of Clinical Chemistry, Karolinska Institutet, Huddinge University Hospital, 141 86 Huddinge, Sweden., Gustafsson JÅ; Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77004, USA., Westerterp M; Department of Medicine, Columbia University, New York, NY 10032, USA., Tall AR; Department of Medicine, Columbia University, New York, NY 10032, USA., Wright SD; CSL Behring, King of Prussia, PA 19406, USA., Espevik T; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway., Schultze JL; German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany., Nickenig G; Medizinische Klinik und Poliklinik II, University Hospital Bonn, 53105 Bonn, Germany., Lütjohann D; Institute of Clinical Chemistry und Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany., Latz E; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway. Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605, USA. eicke.latz@uni-bonn.de.
Source: Science translational medicine [Sci Transl Med] 2016 Apr 06; Vol. 8 (333), pp. 333ra50.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Bode+N%22">Bode N</searchLink>; Medizinische Klinik und Poliklinik II, University Hospital Bonn, 53105 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Halvorsen+B%22">Halvorsen B</searchLink>; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, 0424 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Ulas+T%22">Ulas T</searchLink>; Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Skjelland+M%22">Skjelland M</searchLink>; Department of Neurology, Oslo University Hospital Rikshospitalet, 0424 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22De+Nardo+D%22">De Nardo D</searchLink>; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. 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Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Labzin+LI%22">Labzin LI</searchLink>; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kerksiek+A%22">Kerksiek A</searchLink>; Institute of Clinical Chemistry und Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hempel+C%22">Hempel C</searchLink>; Addi and Cassi Fund, Reno, NV 89511, USA.<br /><searchLink fieldCode="AU" term="%22Heneka+MT%22">Heneka MT</searchLink>; Clinic and Polyclinic for Neurology, University Hospital Bonn, 53105 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hawxhurst+V%22">Hawxhurst V</searchLink>; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+ML%22">Fitzgerald ML</searchLink>; Lipid Metabolism Unit, Center for Computational and Integrative Biology, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Trebicka+J%22">Trebicka J</searchLink>; Medizinische Klinik und Poliklinik I, University Hospital Bonn, 53105 Bonn, Germany. Faculty of Health Sciences, University of Southern Denmark Campusvej 55, DK-5230 Odense M, Denmark.<br /><searchLink fieldCode="AU" term="%22Björkhem+I%22">Björkhem I</searchLink>; Division of Clinical Chemistry, Karolinska Institutet, Huddinge University Hospital, 141 86 Huddinge, Sweden.<br /><searchLink fieldCode="AU" term="%22Gustafsson+JÅ%22">Gustafsson JÅ</searchLink>; Center for Nuclear Receptors and Cell Signaling, University of Houston, Houston, TX 77004, USA.<br /><searchLink fieldCode="AU" term="%22Westerterp+M%22">Westerterp M</searchLink>; Department of Medicine, Columbia University, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Tall+AR%22">Tall AR</searchLink>; Department of Medicine, Columbia University, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Wright+SD%22">Wright SD</searchLink>; CSL Behring, King of Prussia, PA 19406, USA.<br /><searchLink fieldCode="AU" term="%22Espevik+T%22">Espevik T</searchLink>; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Schultze+JL%22">Schultze JL</searchLink>; German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Genomics and Immunoregulation, Life and Medical Sciences Institute, University of Bonn, 53115 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Nickenig+G%22">Nickenig G</searchLink>; Medizinische Klinik und Poliklinik II, University Hospital Bonn, 53105 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Lütjohann+D%22">Lütjohann D</searchLink>; Institute of Clinical Chemistry und Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Latz+E%22">Latz E</searchLink>; Institute of Innate Immunity, University Hospital Bonn, 53127 Bonn, Germany. German Center of Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7489 Trondheim, Norway. Department of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605, USA. eicke.latz@uni-bonn.de.
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