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Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF.

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Title: Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF.
Authors: Mercer PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Woodcock HV; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Eley JD; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Platé M; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Sulikowski MG; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Durrenberger PF; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Franklin L; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Nanthakumar CB; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Man Y; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Genovese F; Nordic Bioscience, Herlev, Denmark., McAnulty RJ; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK., Yang S; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Maher TM; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK., Nicholson AG; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK., Blanchard AD; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Marshall RP; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Lukey PT; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK., Chambers RC; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.
Source: Thorax [Thorax] 2016 Aug; Vol. 71 (8), pp. 701-11. Date of Electronic Publication: 2016 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 0417353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3296 (Electronic) Linking ISSN: 00406376 NLM ISO Abbreviation: Thorax Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exploration of a potent PI3 kinase/mTOR inhibitor as a novel anti-fibrotic agent in IPF.
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  Data: <searchLink fieldCode="AU" term="%22Mercer+PF%22">Mercer PF</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Woodcock+HV%22">Woodcock HV</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Eley+JD%22">Eley JD</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Platé+M%22">Platé M</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Sulikowski+MG%22">Sulikowski MG</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Durrenberger+PF%22">Durrenberger PF</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Franklin+L%22">Franklin L</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Nanthakumar+CB%22">Nanthakumar CB</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Man+Y%22">Man Y</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Genovese+F%22">Genovese F</searchLink>; Nordic Bioscience, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22McAnulty+RJ%22">McAnulty RJ</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Maher+TM%22">Maher TM</searchLink>; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Nicholson+AG%22">Nicholson AG</searchLink>; NIHR Respiratory Biomedical Research Unit, Royal Brompton Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Blanchard+AD%22">Blanchard AD</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Marshall+RP%22">Marshall RP</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Lukey+PT%22">Lukey PT</searchLink>; Department of Fibrosis DPU, Respiratory TA, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+RC%22">Chambers RC</searchLink>; Centre for Inflammation and Tissue Repair, UCL Respiratory, Rayne Institute, University College London, London, UK.
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